Recombinant Anti-EPHA2 Vesicular Antibody, EV Displayed (VS-0425-YC564) (CAT#: VS-0425-YC564)

• Application
• ELISA, FC, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• EPHA2

• Host Animal
• Mouse

• Antibody Isotype
• IgG

• Species Reactivity
• Human

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• Protein A

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• EPH receptor A2

• Biological Process
• Angiogenesis, Apoptosis, Cell adhesion, Differentiation, Host-virus interaction

• Molecular Function
• Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase

• Cellular Localization
• Plasma membrane, Cell Junctions, Nuclear speckles, Golgi apparatus

• Introduction
• This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.

• Alternative Names
• ECK

• Gene ID
• 1969

• UniProt ID
• P29317

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