Human Anti-EPHA2 (clone 3F2) scFv-Fc Chimera
CAT#: VS-0325-FY81
The anti-EPHA2 scFv-Fc antibody targets EPHA2, a receptor tyrosine kinase involved in angiogenesis, cell migration, and cancer progression. It can modulate EPHA2 signaling, potentially affecting vascular and tumor biology. The scFv-Fc format provides high specificity and prolonged half-life, enhancing its utility in research and therapeutic applications.


Specifications
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Specificity
- Human EPHA2
- Species Reactivity
- Human
- Clone
- 3F2
- Applications
- ELISA, Immunofluorescence, Flow Cytometry
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- EPH Receptor A2; Tyrosine-Protein Kinase Receptor ECK; EC 2.7.10.1; ECK; Epithelial Cell Receptor Protein Tyrosine Kinase; Ephrin Type-A Receptor 2; Soluble EPHA2 Variant 1; Epithelial Cell Kinase
- Gene ID
- 1969
- UniProt ID
- P29317
- Long Name
- EPH Receptor A2
- Sequence Similarities
- Belongs to the ephrin receptor subfamily.
- Cellular Localization
- Cell membrane; Cell projection; ruffle membrane; Cell projection; lamellipodium membrane; Cell junction; focal adhesion
- Post Translation Modifications
- Autophosphorylates.
Ubiquitinated by CHIP/STUB1.
Glycosylation at Asn407 and Asn435
Ubiquitination at Lys578
Modification sites at PhosphoSitePlus
Glycosylation from GlyConnect EPHA2_HUMAN (777)
Glycosylation from GlyGen 4 sites, 4 N-linked glycans (1 site), 2 O-linked glycans (2 sites)
- Protein Refseq
- XP_016856026.1; XP_047304215.1; XP_047304223.1; XP_047304228.1; XP_054190833.1
- Function
- Acts as a receptor for hepatitis C virus (HCV) in hepatocytes and facilitates its cell entry.
Mediates HCV entry by promoting the formation of the CD81-CLDN1 receptor complexes that are essential for HCV entry and by enhancing membrane fusion of cells expressing HCV envelope glycoproteins.
Acts as a receptor for human cytomegalovirus (HCMV) to mediate viral entry and fusion in glioblastoma cells.
Customer Review
There are currently no Customer reviews or questions for VS-0325-FY81. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "Clone 3F2"
- CAT
- Product Name
See other products for "EPHA2"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1460z | Mouse Anti-EPHA2 Recombinant Antibody (clone 31G12) | WB, ELISA, ICC, IF | Mouse IgG2b, κ |
HPAB-0450-CN | Mouse Anti-EPHA2 Recombinant Antibody (HPAB-0450-CN) | ELISA, WB, FC, IP | Mouse IgG2a |
ZG-0293J | Mouse Anti-EPHA2 Recombinant Antibody (ZG-0293J) | WB, IHC, ELISA | Mouse IgG |
VS3-CJ94 | Mouse Anti-EPHA2 Recombinant Antibody (VS3-CJ94) | WB, ELISA | Mouse IgG |
VS3-XY629 | Mouse Anti-EPHA2 Recombinant Antibody (clone 1B3C7) | ELISA, WB, IHC | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-381MZ | Anti-Human EPHA2 Recombinant Antibody (LUCA40) | FC | |
TAB-382MZ | Anti-Human EPHA2 Recombinant Antibody (SPL1) | IHC, WB, sELISA | |
TAB-383MZ | Anti-Human EPHA2 Recombinant Antibody (SG5 ) | IHC, WB, sELISA | |
TAB-384MZ | Mouse Anti-EPHA2 Recombinant Antibody (TAB-384MZ) | ELISA | Mouse IgG |
TAB-380MZ-S(P) | Mouse Anti-EPHA2 Recombinant Antibody; scFv Fragment (TAB-380MZ-S(P)) | IHC, WB, sELISA | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-385MZ | Human Anti-EPHA2 Recombinant Antibody (TAB-385MZ) | ELISA | Humanized IgG |
TAB-385MZ-S(P) | Human Anti-EPHA2 Recombinant Antibody; scFv Fragment (TAB-385MZ-S(P)) | ELISA | Humanized scFv |
TAB-385MZ-F(E) | Human Anti-EPHA2 Recombinant Antibody; Fab Fragment (TAB-385MZ-F(E)) | ELISA | Humanized Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-LC145 | PE-A*02:01/Human EphA2 (TLADFDPRV) MHC Tetramer | FCM | |
MHC-LC146 | APC-A*02:01/Human EphA2 (TLADFDPRV) MHC Tetramer | FCM | |
MHC-YF418 | A*02:01/Human EPHA2 (VLAGVGFFI) MHC Pentamer | FCM |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1164 | Hi-Affi™ Rabbit Anti-EPHA2 Recombinant Antibody (clone DS1164AB) | WB | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0336-YC-S(P) | Mouse Anti-EPHA2 Recombinant Antibody; scFv Fragment (HPAB-0336-YC-S(P)) | ELISA, FC, FuncS | Mouse scFv |
HPAB-0337-YC-S(P) | Human Anti-EPHA2 Recombinant Antibody; scFv Fragment (HPAB-0337-YC-S(P)) | ELISA, FC, FuncS | Humanized scFv |
HPAB-0338-YC-S(P) | Human Anti-EPHA2 Recombinant Antibody (clone 2E7); scFv Fragment | ELISA | Human scFv |
HPAB-0339-YC-S(P) | Mouse Anti-EPHA2 Recombinant Antibody (clone EA5); scFv Fragment | ELISA, FC, FuncS | Mouse scFv |
HPAB-0450-CN-S(P) | Mouse Anti-EPHA2 Recombinant Antibody; scFv Fragment (HPAB-0450-CN-S(P)) | ELISA, WB, FC, IP | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-M0068-YC-F(E) | Human Anti-EPHA2 Recombinant Antibody (clone D2-1A7); Fab Fragment | Inhib | Human Fab |
HPAB-M0069-YC-F(E) | Human Anti-EPHA2 Recombinant Antibody (clone TS1); Fab Fragment | FC | Human Fab |
HPAB-M0070-YC-F(E) | Human Anti-EPHA2 Recombinant Antibody (clone Ab2); Fab Fragment | FC | Human Fab |
HPAB-M0071-YC-F(E) | Human Anti-EPHA2 Recombinant Antibody (clone Ab3); Fab Fragment | FC | Human Fab |
HPAB-0526YY-F(E) | Mouse Anti-EPHA2 Recombinant Antibody (clone A-201); Fab Fragment | ELISA, IHC | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0724-XY25 | Rabbit Anti-EPHA2 Agonistic Antibody (VS-0724-XY25) | WB, ELISA, FC, IF, Agonistic assays | Rabbit IgG, kappa |
VS-0724-XY26 | Human Anti-EPHA2 Agonistic Antibody (clone 1C1) | WB, ELISA, FC, IF, Agonistic assays | Human IgG1, kappa |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0424-XY87 | AbPlus™ Anti-EPHA2 Magnetic Beads (VS-0424-XY87) | IP, Protein Purification |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0425-YC564 | Recombinant Anti-EPHA2 Vesicular Antibody, EV Displayed (VS-0425-YC564) | ELISA, FC, Cell-uptake |
Popular Products
Application: FC, Cyt, Stim, PP, Agonist
Application: IF, IP, Neut, FuncS, ELISA, FC, WB
Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
Application: WB, Neut, FuncS
Application: WB, ELISA
Application: ELISA, FC, WB, Block
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA, Inhib, FuncS
Application: Neut
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.