Recombinant Anti-FOLH1 Vesicular Antibody, EV Displayed (VS-0425-YC356)
CAT#: VS-0425-YC356
The Recombinant Anti-FOLH1 Vesicular Antibody, EV Displayed (VS-0425-YC356) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to FOLH1-expressed cells or tissues. The FOLH1 is a glycoprotein that acts on substrates like folate, involved in conditions related to folate deficiencies and prostate cancer.
Gene Expression
Normal Tissue
Figure 1 Kidney
Proximal tubules (microvilli)
Staining: High
Intensity: Strong
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1451/4354_A_7_5.jpg
Normal Tissue
Figure 2 Prostate
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1451/4354_A_2_5.jpg
RNA Expression
Figure 3 RNA cell line category: Cell line enhanced (HAP1, RPMI-8226, SK-BR-3, TIME, WM-115)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000086205-FOLH1
❮
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Recombinant Antibody
- Application
- ELISA, FC, Neut, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- FOLH1
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Folate hydrolase 1
- Molecular Function
- Carboxypeptidase, Dipeptidase, Hydrolase, Metalloprotease, Multifunctional enzyme, Protease
- Introduction
- This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms.
- Alternative Names
- FOLH, GCP2, GCPII, NAALAD1, NAALAdase, PSM, PSMA
- Gene ID
- 2346
- UniProt ID
- Q04609
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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| TAB-274CT-F(E) | Mouse Anti-FOLH1 Recombinant Antibody; Fab Fragment (TAB-274CT-F(E)) | WB, ELISA, FC, IF, IHC | Mouse Fab |
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| TAB-279CT-F(E) | Mouse Anti-FOLH1 Recombinant Antibody; Fab Fragment (TAB-279CT-F(E)) | WB, ELISA, IHC, IF, FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1332 | Hi-Affi™ Rabbit Anti-FOLH1 Recombinant Antibody (clone DS1332AB) | IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0656-CN-S(P) | Mouse Anti-FOLH1 Recombinant Antibody; scFv Fragment (HPAB-0656-CN-S(P)) | WB, IF, FC | Mouse scFv |
| HPAB-M0614-YC-S(P) | Human Anti-FOLH1 Recombinant Antibody; scFv Fragment (HPAB-M0614-YC-S(P)) | ELISA, FC, Cyt, FuncS | Human scFv |
| HPAB-M0092-YC-S(P) | Mouse Anti-FOLH1 Recombinant Antibody scFv Fragment (HPAB-M0092-YC-S(P)) | FC | Mouse scFv |
| HPAB-M0093-YC-S(P) | Human Anti-FOLH1 Recombinant Antibody scFv Fragment (HPAB-M0093-YC-S(P)) | FC | Humanized scFv |
| HPAB-1248WJ-S(P) | Human Anti-FOLH1 Recombinant Antibody (clone 3D8); scFv Fragment | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0184CQ | Human Anti-FOLH1 Recombinant Antibody (HPAB-0184CQ) | ELISA, FC | Human IgG |
| HPAB-0185CQ | Human Anti-FOLH1 Recombinant Antibody (clone YC059) | FC, IHC | Human IgG1, κ |
| MRO-2142-CN | Rabbit Anti-FOLH1 Polyclonal Antibody (MRO-2142-CN) | WB, IF, FC | Rabbit IgG |
| HPAB-M0614-YC | Human Anti-FOLH1 Recombinant Antibody (HPAB-M0614-YC) | ELISA, FC, Cyt, FuncS | Human IgG |
| VS3-XY3359 | Rabbit Anti-FOLH1 Recombinant Antibody (clone R04-6I6) | WB, IHC-P, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-018 | Afuco™ Anti-FOLH1 ADCC Recombinant Antibodyc, ADCC Enhanced (AFC-TAB-018) | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0091-YC-F(E) | Human Anti-FOLH1 Recombinant Antibody; Fab Fragment (HPAB-N0091-YC-F(E)) | ELISA, FC, FuncS, Block | Human Fab |
| HPAB-N0092-YC-F(E) | Human Anti-FOLH1 Recombinant Antibody; Fab Fragment (HPAB-N0092-YC-F(E)) | ELISA, FC | Human Fab |
| HPAB-1130WJ-F(E) | Mouse Anti-FOLH1 Recombinant Antibody (clone J415); Fab Fragment | ELISA | Mouse Fab |
| HPAB-1154WJ-F(E) | Mouse Anti-FOLH1 Recombinant Antibody (clone E99); Fab Fragment | ELISA | Mouse Fab |
| HPAB-1248WJ-F(E) | Human Anti-FOLH1 Recombinant Antibody (clone 3D8); Fab Fragment | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| VS-0525-XY2604 | Anti-Mouse FOLH1 Immunohistochemistry Kit | IHC |
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