Recombinant Anti-ITGB1 Vesicular Antibody, EV Displayed (VS-0425-YC597) (CAT#: VS-0425-YC597)

• Application
• Block, ELISA, FC, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• ITGB1

• Host Animal
• Rat

• Antibody Isotype
• IgG

• Species Reactivity
• Human, Cattle, Pig, Sheep, Horse, Dog, Monkey

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• Protein A

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• Integrin subunit beta 1

• Biological Process
• Cell adhesion, Host-virus interaction, Myogenesis

• Molecular Function
• Host cell receptor for virus entry, Integrin, Receptor

• Cellular Localization
• Plasma membrane, Focal adhesion sites, Endoplasmic reticulum

• Introduction
• Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.

• Alternative Names
• CD29, FNRB, GPIIA, MDF2, MSK12

• Gene ID
• 3688

• UniProt ID
• P05556

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