Anti-human ITGB1 Recombinant Antibody (1B4) (TAB-772LC) (CAT#: TAB-772LC)

Recombinant monoclonal antibody 1B4 is a mouse monoclonal antibody that specifically binds to human Integrin β1 and can be potentially used in the treatment of vascular stenotic and restenotic lesions.

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FuncS

Figure 1 is a quartet of graphs which depict leukocyte counts in animals to which monoclonal antibody 1B4 (triangles) or a control monoclonal antibody (SS1; circles) had been administered.

Figure 1 is a quartet of graphs which depict leukocyte counts in animals to which monoclonal antibody 1B4 (triangles) or a control monoclonal antibody (SS1; circles) had been administered.

FuncS

Figure 2 is a graph which indicates mean anti-monoclonal antibody titers in animals to which monoclonal antibody 1B4 (triangles) or a control monoclonal antibody (circles) had been administered.

Figure 2 is a graph which indicates mean anti-monoclonal antibody titers in animals to which monoclonal antibody 1B4 (triangles) or a control monoclonal antibody (circles) had been administered.

FuncS

Figure 3 depicts blinded quantitative angiography results obtained in test animals.

Figure 3 depicts blinded quantitative angiography results obtained in test animals.

The fig is a graph which shows luminal diameter as a function of time in animals to which monoclonal antibody. 1B4 (squares) or a control monoclonal antibody (circles) had been administered.

FuncS

Figure 4 depicts the results of histomorphometric analysis of intimal area (in square millimeters) obtained from animals to which either monoclonal antibody 1B4 or a control monoclonal antibody had been administered and which had undergone balloon angioplasty (“Balloon Only”) or both balloon angioplasty and endovascular stent emplacement (“Balloon and Stent”).

Figure 4 depicts the results of histomorphometric analysis of intimal area (in square millimeters) obtained from animals to which either monoclonal antibody 1B4 or a control monoclonal antibody had been administered and which had undergone balloon angioplasty (“Balloon Only”) or both balloon angioplasty and endovascular stent emplacement (“Balloon and Stent”).


Specifications

  • Host Species
  • Mouse
  • Specificity
  • Human
  • Clone
  • 1B4
  • Applications
  • FuncS
  • Related Disease
  • Vascular stenotic and restenotic lesions

Applications

  • Application Notes
  • This antibody has been reported for use in Functional Assay.

Target

  • Alternative Names
  • ITGB1; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); CD29; FNRB; MDF2; VLAB; GPIIA; MSK12; VLA-BETA; integrin beta-1; glycoprotein IIa; integrin VLA-4 beta subunit; very late activation protein, beta polypeptide

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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