Anti-human ITGB1 Recombinant Antibody (1B4) (TAB-772LC)

CAT#: TAB-772LC

Recombinant monoclonal antibody 1B4 is a mouse monoclonal antibody that specifically binds to human Integrin β1 and can be potentially used in the treatment of vascular stenotic and restenotic lesions.

Published Data Gene Expression
Figure 1 is a quartet of graphs which depict leukocyte counts in animals to which monoclonal antibody 1B4 (triangles) or a control monoclonal antibody (SS1; circles) had been administered. Figure 2 is a graph which indicates mean anti-monoclonal antibody titers in animals to which monoclonal antibody 1B4 (triangles) or a control monoclonal antibody (circles) had been administered. Figure 3 depicts blinded quantitative angiography results obtained in test animals. Figure 4 depicts the results of histomorphometric analysis of intimal area (in square millimeters) obtained from animals to which either monoclonal antibody 1B4 or a control monoclonal antibody had been administered and which had undergone balloon angioplasty (“Balloon Only”) or both balloon angioplasty and endovascular stent emplacement (“Balloon and Stent”).
Figure 1 IF staining of human cell line BJ Figure 2 IF staining of human cell line BJ Figure 3 Immunofluorescent staining of human cell line BJ Figure 4 Kidney Figure 5 Smooth muscle Figure 6 RNA cell line category: Cell line enhanced (hTERT-RPE1)

Specifications

  • Host Species
  • Mouse
  • Specificity
  • Human
  • Clone
  • 1B4
  • Applications
  • FuncS
  • Related Disease
  • Vascular stenotic and restenotic lesions

Applications

  • Application Notes
  • This antibody has been reported for use in Functional Assay.

Target

  • Alternative Names
  • ITGB1; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); CD29; FNRB; MDF2; VLAB; GPIIA; MSK12; VLA-BETA; integrin beta-1; glycoprotein IIa; integrin VLA-4 beta subunit; very late activation protein, beta polypeptide
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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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COA

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