Recombinant Rabbit Anti-LTA Capture Antibody (clone R02-6Q1) (CAT#: VS3-WK1756)
This antibody is a rabbit recombinant antibody against human LTA. It was developed by immunization of rabbit with recombinant human LTA protein and then was produced as a recombinant antibody. The isotype of this product is rabbit IgG. The sandwich ELISA was established using matched antibody pair R02-6Q1 and R02-5C6. The clone R02-6Q1 can be used as a capture antibody in ELISA analysis to identify human LTA.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Kidney
(Cells in glomeruli
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Cells in tubules
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/7729/28404_A_7_5.jpg
(Cells in glomeruli
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Cells in tubules
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/7729/28404_A_7_5.jpg
Figure 2 Testis
(Cells in seminiferous ducts
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Leydig cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/7729/28404_A_5_6.jpg
(Cells in seminiferous ducts
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Leydig cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/7729/28404_A_5_6.jpg
Figure 3 RNA cell line category: Cell line enhanced (JURKAT, MOLT-4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000226979-LTA
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000226979-LTA
Specifications
- Immunogen
- Recombinant human LTA protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human LTA
- Species Reactivity
- Human
- Clone
- R02-6Q1
- Applications
- ELISA
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Aggregation
- < 5%
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 0.01M PBS, pH 7.2
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- LT; TNFB; TNFSF1; TNLG1E
- Gene ID
- 4049
- UniProt ID
- P01374
- Long Name
- Lymphotoxin alpha
- Sequence Similarities
- Belongs to the tumor necrosis factor family.
- Cellular Localization
- Membrane, Secreted
- Protein Refseq
- NP_000586.2
- Function
- Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM.
In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo.
Recommended Products
Detection antibody
Isotype Control
Secondary Antibody
Related Resources
TNF Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Single Domain Antibody Products
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ADCC Enhanced Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-2017-sdAb | Recombinant Anti-LTA VHH Single Domain Antibody | WB, ICC, ChiP, FA, ELISA | Llama VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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