Recombinant Anti-NT5E Vesicular Antibody, EV Displayed (VS-0425-YC110) (CAT#: VS-0425-YC110)

• Application
• ELISA, FC, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• NT5E

• Host Animal
• Human

• Antibody Isotype
• IgG1

• Species Reactivity
• Mouse, Cynomolgus

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• z domain

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Binding Affinity
• Kd = 0.85 µg/mL

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• 5'-nucleotidase ecto

• Molecular Function
• Hydrolase

• Cellular Localization
• Plasma membrane, Nucleoplasm, Cytosol

• Introduction
• This gene encodes a membrane-bound nucleotidase that hydrolyzes extracellular nucleoside monophosphates. The encoded preproprotein undergoes proteolytic processing to generate to a functional, homodimeric enzyme that preferentially uses adenosine monophosphate as a substrate to generate free adenosine. Mice lacking the encoded protein exhibit a significantly reduced fall in stop flow pressure and superficial nephron glomerular filtration rate in response to a saturating increase of tubular perfusion flow.

• Alternative Names
• NT; Nt5; eNT; CD73; 5'-NT; 2210401F01Rik

• Gene ID
• 23959

• UniProt ID
• Q3U3S1

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