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APP

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This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease.

Derivation:
Humanized (from mouse)
Species Reactivity:
Human
Type:
IgG1
Application:
WB, FuncS, IF, Neut, ELISA, FC, IP
Derivation:
Humanized (from mouse)
Species Reactivity:
Human
Type:
IgG4 - kappa
Application:
WB, IF, IP, Neut, FuncS, ELISA, FC
Derivation:
Human
Species Reactivity:
Human
Type:
IgG1 - kappa
Application:
Neut, ELISA, IF, IP, FuncS, FC, ICC
Derivation:
Humanized (from mouse)
Species Reactivity:
Human
Type:
IgG1 - kappa
Application:
WB, FuncS, IF, Neut, ELISA, FC, IP
Derivation:
Humanized (from mouse)
Species Reactivity:
Human
Type:
IgG2 - kappa
Application:
WB, ELISA, IP, FC, FuncS, Neut, IF
Derivation:
Human
Species Reactivity:
Human
Type:
IgG1 - kappa
Application:
FuncS, IF, Neut, ELISA, FC, IP, ICC
Derivation:
Humanized
Species Reactivity:
Human
Type:
ADCC enhanced antibody
Derivation:
Mouse
Species Reactivity:
Human
Type:
Fab
Application:
WB, IF, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
Fab
Application:
WB, ELISA, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
IgG
Application:
ELISA, WB, IF, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
Fab
Application:
IF, FC, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
scFv
Application:
WB, Neut, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
scFv
Application:
WB, IF, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
scFv
Application:
WB, ELISA, FuncS
Derivation:
Human
Species Reactivity:
Human
Type:
scFv
Application:
WB, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
scFv
Application:
WB, ELISA, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
Fab
Application:
WB
Derivation:
Mouse
Species Reactivity:
Human
Type:
Fab
Application:
WB
Derivation:
Mouse
Species Reactivity:
Human
Type:
Fab
Application:
ELISA
Derivation:
Humanized
Species Reactivity:
Human
Type:
Antibody
Scaffold Name:
Z-domain of protein A
Target:
Human amyloid beta (Aβ) peptides
Species Reactivity:
Human
Derivation:
Phage display
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