APP
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ELISA, FuncS
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: WB, FuncS, IF, Neut, ELISA, FC, IP
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- Derivation: Human
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
- Human Anti-APP Recombinant Antibody (TAB-0829CLV) (TAB-0829CLV)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized antibody
- Application: ELISA
- Human Anti-APP Recombinant Antibody (TAB-0830CLV) (TAB-0830CLV)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized antibody
- Application: ELISA
- Human Anti-APP Recombinant Antibody (TAB-0831CLV) (TAB-0831CLV)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized antibody
- Application: ELISA
- Anti-Human APP Recombinant Antibody (AD38) (TAB-0841CLV)
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- Derivation: Peripheral blood B cell
- Type: Human antibody
- Anti-Human APP Recombinant Antibody (AD64) (TAB-0842CLV)
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- Derivation: Peripheral blood B cell
- Type: Human antibody
- Human Anti-APP Recombinant Antibody; scFv Fragment (TAB-253CQ-S(P)) (TAB-253CQ-S(P))
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- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA
- Mouse Anti-APP Recombinant Antibody; scFv Fragment (TAB-254CQ-S(P)) (TAB-254CQ-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
- Human Anti-APP Recombinant Antibody (TAB-253CQ) (TAB-253CQ)
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- Species Reactivity: Human
- Type: Humanized IgG1
- Application: ELISA
- Human Anti-APP Recombinant Antibody (TAB-254CQ) (TAB-254CQ)
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- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG1
- Application: ELISA
- Anti-APP Recombinant Antibody (C706) (TAB-0767CLV)
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- Anti-APP Recombinant Antibody (C705) (TAB-0768CLV)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: ELISA
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: IF, FuncS
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: WB
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: ELISA
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, ELISA, FuncS
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a, κ
- Application: WB, IF, FuncS
- Mouse Anti-APP Recombinant Antibody (clone 25F3) (MOB-1185z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, FC, ICC, IF, IHC
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG4 - kappa
- Application: WB, IF, IP, Neut, FuncS, ELISA, FC
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG2 - kappa
- Application: WB, ELISA, IP, FC, FuncS, Neut, IF
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: ELISA
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- Derivation: Human
- Species Reactivity: Human
- Type: Human IgG2, κ
- Application: WB, FuncS
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, ELISA, FuncS
- Human Anti-APP Recombinant Antibody (TAB-0343CL) (TAB-0343CL)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, Inhib
- Human Anti-APP Recombinant Antibody (TAB-0344CL) (TAB-0344CL)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
- Anti-APP Recombinant Antibody (22C4) (TAB-0846CLV)
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- Anti-APP Recombinant Antibody Fab Fragment (C706) (TAB-0767CLV-F(E))
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- Anti-APP Recombinant Antibody Fab Fragment (C705) (TAB-0768CLV-F(E))
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG1
- Application: WB, FuncS, IF, Neut, ELISA, FC, IP
- Mouse Anti-APP Recombinant Antibody; scFv Fragment (TAB-0772CLV-S(P)) (TAB-0772CLV-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
- Anti-Human APP Recombinant Antibody (2B3) (TAB-0847CLV)
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- Application: WB, ELISA
- Anti-Human APP Recombinant Antibody (2B12) (TAB-0848CLV)
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- Application: WB, ELISA
- Mouse Anti-APP Recombinant Antibody (TAB-0849CLV) (TAB-0849CLV)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB, DB
- Mouse Anti-APP Recombinant Antibody (TAB-0850CLV) (TAB-0850CLV)
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- Species Reactivity: Human
- Type: Mouse IgG3
- Application: ELISA, WB, DB
- Mouse Anti-APP Recombinant Antibody (TAB-0851CLV) (TAB-0851CLV)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ICC, IF, ICC
- Mouse Anti-APP Recombinant Antibody; Fab Fragment (TAB-0764CLV-F(E)) (TAB-0764CLV-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
- Mouse Anti-APP Recombinant Antibody; Fab Fragment (TAB-0765CLV-F(E)) (TAB-0765CLV-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
- Mouse Anti-APP Recombinant Antibody; Fab Fragment (TAB-0766CLV-F(E)) (TAB-0766CLV-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
- Camelid Anti-APP Recombinant Antibody (TAB-0019CL-VHH) (TAB-0019CL-VHH)
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- Species Reactivity: Human
- Type: Camelid VHH
- Application: IHC, WB
- Anti-Human APP VHH Single Domain Antibody (TAB-0020CL-VHH) (TAB-0020CL-VHH)
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- Type: Single domain antibody
- Application: ELISA, IHC
- Anti-Human APP VHH Single Domain Antibody (TAB-0021CL-VHH) (TAB-0021CL-VHH)
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- Type: Single domain antibody
- Application: ELISA, In vivo, FuncS
- Anti-Human APP VHH Single Domain Antibody (TAB-0022CL-VHH) (TAB-0022CL-VHH)
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- Type: Single domain antibody
- Application: ELISA, In vivo, FuncS
- Anti-Human APP VHH Single Domain Antibody (TAB-0023CL-VHH) (TAB-0023CL-VHH)
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- Type: Single domain antibody
- Application: ELISA, In vivo, FuncS
- Mouse Anti-APP Recombinant Antibody (TAB-255CQ) (TAB-255CQ)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB
- Mouse Anti-APP Recombinant Antibody; scFv Fragment (TAB-252CQ-S(P)) (TAB-252CQ-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, ELISA, FuncS
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- Derivation: Human
- Species Reactivity: Human
- Type: Human scFv
- Application: WB, FuncS
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, ELISA, FuncS
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB, ELISA, FuncS
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- Derivation: Llama
- Species Reactivity: Human
- Type: Llama VHH
- Application: WB, ELISA, FuncS
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- Derivation: Llama
- Species Reactivity: Human
- Type: Llama VHH
- Application: ELISA, Neut, WB, Inhibition
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, ELISA, FuncS
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: ELISA
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB, ELISA, FuncS
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- Derivation: Human
- Species Reactivity: Human
- Type: Human Fab
- Application: WB, FuncS
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, IF, FuncS
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB, IF, FuncS
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- Derivation: Llama
- Species Reactivity: Human
- Type: Llama VHH
- Application: WB, ELISA, FuncS
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- Scaffold Name: Z-domain of protein A
- Target: Human amyloid beta (Aβ) peptides
- Species Reactivity: Human
- Derivation: Phage display
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: ELISA
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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- Species Reactivity: Human
- Type: Llama VHH
- Application: CA, IP, IF, FuncS
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB, ELISA, FuncS
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
- Anti-Human APP Recombinant Antibody (TAB-0010CL)
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- Application: ELISA, Block, FuncS, ELISA
- Anti-Human APP Recombinant Antibody scFv Fragment (TAB-0010CL-S(P))
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- Application: ELISA, Block, FuncS
- Mouse Anti-APP Recombinant Antibody; scFv Fragment (TAB-0341CL-S(P)) (TAB-0341CL-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FuncS, In vivo
- Mouse Anti-APP Recombinant Antibody; scFv Fragment (TAB-0342CL-S(P)) (TAB-0342CL-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FuncS, In vivo
- Mouse Anti-APP Recombinant Antibody; Fab Fragment (TAB-0341CL-F(E)) (TAB-0341CL-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FuncS, In vivo
- Anti-Human APP VHH Single Domain Antibody (TAB-0024CL-VHH) (TAB-0024CL-VHH)
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- Type: Single domain antibody
- Application: ELISA, In vivo, FuncS
- Anti-Human APP VHH Single Domain Antibody (TAB-0025CL-VHH) (TAB-0025CL-VHH)
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- Type: Single domain antibody
- Application: ELISA, In vivo, FuncS
- Anti-Human APP VHH Single Domain Antibody (TAB-0026CL-VHH) (TAB-0026CL-VHH)
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- Type: Single domain antibody
- Application: ELISA, In vivo, FuncS
- Anti-Human APP VHH Single Domain Antibody (TAB-0027CL-VHH) (TAB-0027CL-VHH)
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- Type: Single domain antibody
- Application: ELISA, In vivo, FuncS
- Anti-Human APP VHH Single Domain Antibody (TAB-0028CL-VHH) (TAB-0028CL-VHH)
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- Type: Single domain antibody
- Application: ELISA, In vivo, FuncS
- Anti-Human APP VHH Single Domain Antibody (TAB-0029CL-VHH) (TAB-0029CL-VHH)
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- Type: Single domain antibody
- Application: ELISA, In vivo, FuncS
- Anti-Human APP VHH Single Domain Antibody (TAB-0030CL-VHH) (TAB-0030CL-VHH)
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- Type: Single domain antibody
- Application: ELISA, In vivo, FuncS
- Anti-Human APP VHH Single Domain Antibody (TAB-0031CL-VHH) (TAB-0031CL-VHH)
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- Type: Single domain antibody
- Application: ELISA, In vivo, FuncS
- Mouse Anti-APP Recombinant Antibody (TAB-252CQ) (TAB-252CQ)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA
- Mouse Anti-APP Recombinant Antibody; Fab Fragment (TAB-252CQ-F(E)) (TAB-252CQ-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
- Mouse Anti-APP Recombinant Antibody (TAB-0769CLV) (TAB-0769CLV)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
- Mouse Anti-APP Recombinant Antibody (TAB-0770CLV) (TAB-0770CLV)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
- Mouse Anti-APP Recombinant Antibody; scFv Fragment (TAB-255CQ-S(P)) (TAB-255CQ-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
- Mouse Anti-APP Recombinant Antibody (TAB-0764CLV) (TAB-0764CLV)
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- Species Reactivity: Human
- Type: Mouse IgG3
- Application: ELISA
- Mouse Anti-APP Recombinant Antibody (TAB-0765CLV) (TAB-0765CLV)
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- Species Reactivity: Human
- Type: Mouse IgM
- Application: ELISA
- Mouse Anti-APP Recombinant Antibody (TAB-0766CLV) (TAB-0766CLV)
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- Species Reactivity: Human
- Type: Mouse IgM
- Application: ELISA
- Anti-APP Recombinant Antibody (RCK37) (TAB-0843CLV)
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- Anti-APP Recombinant Antibody (RCK22) (TAB-0844CLV)
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- Anti-APP Recombinant Antibody (37H) (TAB-0845CLV)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
- Mouse Anti-APP Recombinant Antibody (TAB-0840CLV) (TAB-0840CLV)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: FuncS, IHC, ELISA
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2014]