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APP
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
Anti-Human APP Therapeutic Antibody scFv Fragment (AM 2.9) (TAB-0341CL-S(P))
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- Application: For in vitro and in vivo research use. Not intended for any applications in human.
Anti-Human APP Therapeutic Antibody scFv Fragment (TAB-0010CL-S(P))
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- Application: For in vitro and in vivo research use. Not intended for any applications in human.
Anti-Human APP Therapeutic Antibody (AM 3.26) (TAB-0342CL)
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- Application: For in vitro and in vivo research use. Not intended for any applications in human.
Recombinant Mouse Anti-APP Antibody scFv Fragment (c706) (PSBL-400)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: ELISA
Recombinant Mouse Anti-APP Antibody Fab Fragment (WO2) (PFBL-401)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: WB, ELISA, FuncS
Anti-Human APP Therapeutic Antibody (AM 2.9) (TAB-0341CL)
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- Application: For in vitro and in vivo research use. Not intended for any applications in human.
Anti-Human APP Therapeutic Antibody (TAB-0010CL)
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- Application: For in vitro and in vivo research use. Not intended for any applications in human.
Recombinant Mouse Anti-APP Antibody scFv Fragment (12B4) (PSBL-399)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: WB
Recombinant Mouse Anti-APP Antibody Fab Fragment (c706) (PFBL-400)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: ELISA
Recombinant Mouse Anti-APP Antibody (WO2) (PABL-404)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: WB, ELISA, FuncS
Recombinant Mouse Anti-APP Antibody scFv Fragment (10D5) (PSBL-398)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: WB
Recombinant Mouse Anti-APP Antibody scFv Fragment (PFA2) (PSBC-010)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: ELISA
Recombinant Mouse Anti-APP Antibody Fab Fragment (12B4) (PFBL-399)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: WB
Recombinant Mouse Anti-APP Antibody (c706) (PABL-403)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: ELISA
Recombinant Mouse Anti-APP Antibody scFv Fragment (PFA1) (PSBW-009)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: ELISA
Recombinant Mouse Anti-APP Antibody Fab Fragment (PFA2) (PFBC-010)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: ELISA
Recombinant Mouse Anti-APP Antibody Fab Fragment (10D5) (PFBL-398)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: WB
Recombinant Mouse Anti-APP Antibody (12B4) (PABL-402)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: WB
Recombinant Mouse Anti-APP Antibody (PFA2) (PABC-010)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: ELISA
Recombinant Mouse Anti-APP Antibody Fab Fragment (PFA1) (PFBW-009)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: ELISA
Recombinant Mouse Anti-APP Antibody (12B4) (PABW-151)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: WB
Recombinant Mouse Anti-APP Antibody (10D5) (PABL-401)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: WB
Recombinant Mouse Anti-APP Antibody (PFA1) (PABW-009)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: ELISA
Recombinant Anti-APP VHH Single Domain Antibody (KW1) (PNBL-070)
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- Derivation: Llama
- Species Reactivity: Human
- Type: Llama VHH
- Application: ELISA, Neut, WB, Inhibition
Recombinant Mouse Anti-APP Antibody Fab Fragment (C705) (PFBL-013)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: WB, ELISA, FuncS
Recombinant Mouse Anti-APP Antibody scFv Fragment (C705) (PSBL-013)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: WB, ELISA, FuncS
Recombinant Mouse Anti-APP Antibody (C705) (PABL-013)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: WB, ELISA, FuncS
Recombinant Anti-Human APP VHH Single Domain Antibody (PS2-8) (PNBL-004)
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- Derivation: Llama
- Species Reactivity: Human
- Type: Llama VHH
- Application: WB, ELISA, FuncS
Recombinant Human Anti-APP Antibody Fab Fragment (9TL) (PFBL-012)
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- Derivation: Human
- Species Reactivity: Human
- Type: Fab
- Application: WB, FuncS
Recombinant Human Anti-APP Antibody scFv Fragment (9TL) (PSBL-012)
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- Derivation: Human
- Species Reactivity: Human
- Type: scFv
- Application: WB, FuncS
Recombinant Human Anti-APP Antibody (9TL) (PABL-012)
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- Derivation: Human
- Species Reactivity: Human
- Type: IgG
- Application: WB, FuncS
Recombinant Anti-Human APP VHH Single Domain Antibody (G7) (PNBL-003)
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- Derivation: Llama
- Species Reactivity: Human
- Type: Llama VHH
- Application: WB, ELISA, FuncS
Recombinant Mouse Anti-APP Antibody Fab Fragment (3D6) (PFBL-011)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: WB, ELISA, FuncS
Recombinant Mouse Anti-APP Antibody scFv Fragment (3D6) (PSBL-011)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: WB, ELISA, FuncS
Recombinant Mouse Anti-APP Antibody (3D6) (PABL-011)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: WB, ELISA, FuncS
Afuco™ Anti-Human APP ADCC Therapeutic Antibody (BAN2401), ADCC Enhanced (AFC-050CL)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: ADCC enhanced antibody
Anti-Human APP Therapeutic Antibody (BAN2401) (TAB-052CL)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Antibody
- Application: PK
Anti-Human Abeta Therapeutic Antibody (Gantenerumab) (TAB-229)
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- Derivation: Human
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
Anti-Human Abeta Therapeutic Antibody (Crenezumab) (TAB-226)
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG4 - kappa
- Application: WB, IF, IP, Neut, FuncS, ELISA, FC
Anti-Human Abeta Therapeutic Antibody (Ponezumab) (TAB-227)
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG2 - kappa
- Application: WB, ELISA, IP, FC, FuncS, Neut, IF
Recombinant Anti-Human APP Antibody scFv Fragment (MOB-1185z-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: WB, Neut, FuncS
Recombinant Anti-Human APP Antibody Fab Fragment (MOB-1185z-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: IF, FC, FuncS
Anti-Human Abeta Therapeutic Antibody (Solanezumab) (TAB-228)
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: WB, FuncS, IF, Neut, ELISA, FC, IP
Anti-Human Abeta Therapeutic Antibody (Bapineuzumab) (TAB-225)
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG1
- Application: WB, FuncS, IF, Neut, ELISA, FC, IP
Recombinant Anti-Human APP VHH Single Domain Antibody (NABG-016)
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- Species Reactivity: Human
- Type: Llama VHH
- Application: CA, IP, IF, FuncS
Recombinant Anti-Human APP Antibody (MOB-1185z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: ELISA, WB, IF, FuncS
Recombinant Mouse Anti-APP Antibody Fab Fragment (12A11 ) (PFBL-010)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: WB, IF, FuncS
Recombinant Mouse Anti-APP Antibody scFv Fragment (12A11 ) (PSBL-010)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: WB, IF, FuncS
Recombinant Mouse Anti-APP Antibody (12A11 ) (PABL-010)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: WB, IF, FuncS
Recombinant Mouse Anti-APP Antibody scFv Fragment (WO2) (PSBL-401)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: WB, ELISA, FuncS
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