Anti-CAMK1 Recombinant Antibody Products

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Anti-CAMK1 Products

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For Research Use Only. Not For Clinical Use.


Creative Biolabs is a trusted pioneer in cell signaling research, offering you our elite anti-CAMK1 recombinant antibodies. Calcium/Calmodulin Dependent Protein Kinase 1 (CAMK1) is an important downstream effector of the calcium/calmodulin signaling pathway and is important for transcriptional regulation and cell differentiation. We have isoform-specific, high-quality antibodies for dissecting the unique functions of this important kinase.

CAMK1: A Downstream Effector of Calcium Signaling

Calcium/Calmodulin Dependent Protein Kinase 1 (CAMK1), also known as CAMK I, is a serine/threonine kinase and member of the CaMK family of proteins. CAMK1 is activated through phosphorylation on its T-loop by upstream kinases CAMKK1 and CAMKK2 in response to elevated cytoplasmic calcium levels. CAMK1 phosphorylates a number of downstream targets, including transcription factors to regulate gene expression. It has been implicated in a number of cell signaling pathways, including T-cell activation, neuronal differentiation, and hormone signaling.

Alternative Names

CAMKI

Background

CAMK1 (Calcium/Calmodulin Dependent Protein Kinase I) is a Protein Coding gene. Some of its related pathways include NFAT and Cardiac Hypertrophy and Neuropathic Pain-Signaling in Dorsal Horn Neurons. Some of the Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is CAMK1D.

Protein class

Enzymes, Metabolic proteins, Plasma proteins

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (Hofbauer cells, Macrophages, Sertoli cells, Adipocytes)

Immune cell specificity

Immune cell enriched (eosinophil)

Cell line specificity

Cell line enriched (HMC-1)

Interaction

Monomer. Interacts with XPO1 (By similarity). Interacts with MARK2, ARHGEF7/BETAPIX and GIT1.

Molecular function

Allosteric enzyme, Calmodulin-binding, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase

More Types Infomation

Anti-CAMK1 rAb Products

Our high-quality recombinant anti-CAMK1 antibodies are engineered to provide unparalleled specificity and have been thoroughly validated in assays like Western Blot and kinase assays to detect CAMK1 without cross-reactivity to other family members like CAMK2 or CAMK4. This high specificity is crucial to the study of its distinct cellular functions. Optimized for use in cell signaling research, our rAbs are a reliable and precise tool for unraveling the complexities of this signaling molecule.

Table 1. Featured anti-CAMK1 recombinant antibody products at Creative Biolabs.

Cat. No. Product Name Target Species Host Species Applications
VS3-FY1632 Rabbit Anti-CAMK1 Recombinant Antibody (clone R06-7C4) Human, Mouse, Rat Rabbit IgG WB
MOB-3291z Mouse Anti-CAMK1 Recombinant Antibody (clone 40G3) Human Mouse IgG1, κ WB, IP, IF, ELISA

Creative Quality Control

Creative Biolabs takes scientific quality and integrity to the highest standard. We back the production of our anti-CAMK1 recombinant antibodies with a comprehensive quality assurance protocol. Every lot is validated for purity, isoform specificity, and performance in recommended applications so you know you're getting a reliable reagent for your important work.

Fig.1 WB analysis. (Creative Biolabs Original)Fig.1 WB analysis of anti-CAMK1 antibody (Cat# VS3-FY1632, Creative Biolabs).

Customer Reviews

Excellent
E**an
Mouse Anti-CAMK1 Recombinant Antibody (clone 40G3)
The quality of Creative Biolabs' antibodies is excellent. This anti-CAMK1 antibody has performed very consistently, which is critical for the long-term studies that we do on calcium signaling.
11/Nov/2024

rAb Production

Creative Biolabs leverages cutting-edge platforms to support the specialized field of signal transduction. We express our recombinant antibodies, including anti-CAMK1 rAbs, in optimized systems for superior antibody production. This means the antibodies accurately recognize the native kinase to provide you with a highly specific, active antibody for your experiments.

Featured Anti-CAMK1 Recombinant Antibody Production PlatformsFig.2 Milligram-scale. (Creative Biolabs Original)
Fig.2 Milligram-scale anti-CAMK1 recombinant antibody production.

Fig.3 Gram-scale. (Creative Biolabs Original)Fig.3 Gram-scale anti-CAMK1 recombinant antibody production.

rAb Modalities

Creative Biolabs is passionate about empowering innovation and discovery. This is why we offer a flexible range of antibody modalities to help you move your research forward. Our recombinant antibodies, including this anti-CAMK1 antibody, are available in a number of customizable formats, such as phospho-specific.

Fig.4 CAMK1 antibody production and modalities. (Creative Biolabs Original)Fig.4 Full-length anti-CAMK1 recombinant antibody production and modalities.

Dissect CAMK1 function with the highest quality antibodies from Creative Biolabs. Our recombinant antibody portfolio is designed to provide isoform-specific, thoroughly validated products to help support your research. Connect with our experts to partner with a company that delivers quality that knows no bounds.

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