CR2
Anti-CR2 Recombinant Antibody Products
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: FC, IF
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: FC, IF
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- Species Reactivity: Human
- Type: Mouse IgG1
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- Species Reactivity: Human
- Type: Mouse IgG1
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- Species Reactivity: Human
- Type: Mouse IgG1
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- Type: Mouse IgG1
- Application: ELISA, FC
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: IF, FC
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- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: IHC-P
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: IHC-P
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB
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- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, ICC, IHC, IP, FC
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: FC, IF
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- Species Reactivity: Human
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: IHC-P, IF
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: IHC-P, IF
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- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG
- Application: IHC-P, IF/ICC
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA, WB, IHC, IF, FC
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IHC-P
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IF, IHC, FC
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- Species Reactivity: Human, Primate
- Type: Mouse IgG1
- Application: FC, Inhib, WB
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- Species Reactivity: Mouse
- Type: Mouse IgG1, κ
- Application: WB, ELISA, FC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: IHC, FC, ELISA
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- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG
- Application: IHC, IF
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: IHC-P
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- Derivation: Mouse
- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG
- Application: ELISA, IHC
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- Target: CR2
- Target Species: Human, Cynomolgus
- Application: IP, Protein Purification
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IHC
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: IHC
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- Species Reactivity: Mouse
- Type: Rabbit IgG
- Application: WB, Neut, FC, IHC-Fr, IP, CyTOF®
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- Class: Class I
- Antigen: CR2
- Antigen Species: Human
- Peptide: VSYGSIVTY
- Conjugate: PE
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- Species Reactivity: Bovine
- Type: Mouse IgG
- Application: FC, IP
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- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, IF, IHC, IP, FC
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- Species Reactivity: Mouse
- Type: Mouse Fab
- Application: FC, WB, ELISA, FuncS
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- Species Reactivity: Mouse
- Type: Mouse scFv
- Application: FC, WB, ELISA, FuncS
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse IgG1, kappa
- Application: FC
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- Species Reactivity: Human, Rhesus, Cynomolgus, Baboon
- Type: Mouse IgG1, kappa
- Application: FC
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- Target: CD21
- Linker: mcc (Maleimidomethyl cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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- Target: CD21
- Linker: SPP(N-succinimidyl-4-(2-pyridyldithio)pentanoate)
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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- Target: CD21
- Linker: MCC(Maleimidomethyl cyclohexane-1-carboxylate)
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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- Target: CD21
- Linker: mc-VC-PABC(maleimidocaproyl valine-citrulline-p-aminobenzyl carbamoyl)
- Drug: MMAE (monomethyl auristatin E)
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- Target: CD21
- Linker: mc(maleimidocaproyl)
- Drug: MMAF (monomethyl auristatin F)
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For Research Use Only. Not For Clinical Use.
CR2 is a gene encoding a receptor that plays a significant role in B cell activation and immune responses. It is part of the complement receptor family and binds to complement component C3d. CR2 is expressed primarily on B cells, as well as on some T cells and dendritic cells. It helps in the activation of B cells upon antigen binding and is crucial for the proper functioning of the adaptive immune system. Defects in CR2 may impair immune response and contribute to autoimmune diseases, including systemic lupus erythematosus (SLE).