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    CYCS

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    For Research Use Only. Not For Clinical Use.


    This gene encodes a small heme protein that functions as a central component of the electron transport chain in mitochondria. The encoded protein associates with the inner membrane of the mitochondrion where it accepts electrons from cytochrome b and transfers them to the cytochrome oxidase complex. This protein is also involved in initiation of apoptosis. Mutations in this gene are associated with autosomal dominant nonsyndromic thrombocytopenia. Numerous processed pseudogenes of this gene are found throughout the human genome.
    Protein class

    Disease related genes, Human disease related genes, Plasma proteins

    Predicted location

    Intracellular

    Single cell type specificity

    Cell type enhanced (Distal tubular cells)

    Immune cell specificity

    Low immune cell specificity

    Cell line specificity

    Low cell line specificity

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