FcγRI & LDL

Low-density lipoprotein (LDL) is one of the five major groups of lipoproteins. Lipoproteins are complex particles composed of multiple proteins which transport all fat molecules (lipids) around the body within the water outside cells. They are typically composed of 80-100 proteins/particle (organized by a single ApoB for LDL and the larger particles) and transporting about 3,000 to 6,000 fat molecules/particle. The fats carried include cholesterol, phospholipids, and triglycerides; amounts of each quite variable.

This gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1.