Anti-GHR Recombinant Antibody Products

Creative Biolabs provides an extensive selection of high-quality anti-GHR recombinant antibodies that are expertly designed to achieve outstanding performance. Based on our advanced technology and platforms, we guarantee remarkable specificity, durability, and effectiveness, making these antibodies essential tools for researchers and developers focused on targeted cancer treatment.

GHR: An Essential Target for Cancer Treatment

The growth hormone receptor (GHR) is a versatile member of the class I cytokine receptor family, influencing various biological processes beyond growth regulation. It plays a significant role in metabolic control, as well as the functioning of vital organs such as the liver, heart, kidneys, intestines, and reproductive system. Notably, GHR signaling impacts aging and cancer development. Excessive GHR activation has been linked to the onset of cancers like colorectal, prostate, and breast cancer. Therefore, targeting GHR offers a promising approach for developing effective cancer therapeutics.

Alternative Names

Growth hormone receptor; GHBP; GHIP; GH receptor; growth hormone binding protein; serum binding protein; somatotropin receptor.

Background

This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. The binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.

Anti-GHR rAb Products

Creative Biolabs offers a wide range of anti-GHR recombinant antibodies that have been precisely developed to improve research in endocrinology and therapeutic fields. These antibodies feature excellent specificity and affinity for GHR, making them ideal for studying growth hormone signaling pathways and their relevance to illnesses including growth abnormalities, metabolic syndromes, and certain malignancies. In addition, these antibodies are generated through cutting-edge methods, which provide constant quality and repeatability. Our anti-GHR recombinant antibodies are also available in a variety of forms, making them suitable for a wide range of applications like ELISA, Western blotting, immunohistochemistry, and flow cytometry.

Table 1. Featured anti-GHR recombinant antibody products at Creative Biolabs.

Creative Quality Control

Creative Biolabs provides a broad selection of recombinant antibodies targeting the Growth Hormone Receptor (GHR), precisely manufactured in our cutting-edge laboratory. Our experienced researchers employ modern methodologies to customize each antibody for maximum accuracy and efficacy in targeting GHR. Through extensive testing and validation processes, we guarantee that our antibodies demonstrate exceptional specificity, robust binding affinity, and advantageous optical characteristics, making them suitable for various research applications.

Customer Reviews

Excellent

Fa***d
Recombinant Rabbit Anti-GHR Antibody (clone R02-6E6) (VS3-FY593)

The Anti-GHR Recombinant Antibody from Creative Biolabs has proven to be an invaluable tool for our Western Blot and Immunoprecipitation experiments. Its high specificity and sensitivity allowed for the clear detection and precise quantification of GHR protein expression. Additionally, the antibody's strong binding affinity facilitated efficient immunoprecipitation of GHR protein complexes, enabling further downstream analysis. We are highly satisfied with the quality and performance of this antibody, and it has significantly contributed to the success of our research.

7/Nov/2021

Excellent

Me***a
Rabbit Anti-GHR Recombinant Antibody (clone 10C11) (ZG-0687J)

I purchased the anti-GHR recombinant antibody to perform the IHC assay. This antibody showcases impressive specificity and sensitivity, facilitating accurate detection of GHR expression across diverse tissue samples. The staining was remarkably consistent, with low background interference, which greatly contributed to the overall clarity of our immunohistochemical findings.

18/Jul/2022

Excellent

Br***s
Mouse Anti-GHR Recombinant Antibody (clone 43A10) (MOB-2404z)

The Anti-GHR Recombinant Antibody from Creative Biolabs has been instrumental in our neutralization assays. Its high affinity and specificity for GHR enabled us to effectively block GHR signaling and assess the impact on cellular responses. The antibody's robust performance in neutralization assays has significantly advanced our research, providing valuable insights into the role of GHR in various biological processes.

13/Mar/2024

rAb Production

Creative Biolabs offers a reliable range of high-quality anti-GHR antibodies, crafted through advanced genetic technologies to ensure exceptional performance and consistency.

Featured Anti-GHR Recombinant Antibody Production Platforms
Fig.5 Milligram-scale anti-GHR recombinant antibody production.

Fig.6 Gram-scale anti-GHR recombinant antibody production.

rAb Modalities

Creative Biolabs offers a comprehensive selection of premium anti-GHR recombinant antibodies available in various formats, tailored to satisfy the diverse needs of researchers around the world.

Fig.7 Full-length anti-GHR recombinant antibody production and modalities.

GHR-Targeted Drug Information

Table 2. Public drug targeting GHR.

(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)

Whether you are conducting research in the fields of endocrinology, developmental biology, or related areas, our anti-GHR antibodies are designed to provide exceptional performance and reliability. For further information or inquiries regarding our specialized anti-GHR recombinant antibody products, please don't hesitate to reach out to us at your convenience.