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    Anti-Human GHR Recombinant Antibody Fab Fragment (Ab13) (CAT#: TAB-089CQ-F(E))

    Recombinant monoclonal antibody to GHR. The antibody that selectively interacts with and inhibits human GHR function can reduce IGF-1 levels and can be potentially used in the treatment of arthritis.

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    • Endotoxin:

    • Purity:

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    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
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    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line U-2 OS
    Figure 1 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane, cytosol & cytoplasmic bodies.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57705/1366_E6_2_selected.jpg
    Figure 2 IF staining of human cell line HEK 293
    Figure 2 IF staining of human cell line HEK 293
    (Immunofluorescent staining of human cell line HEK 293 shows localization to plasma membrane, cytosol & cytoplasmic bodies.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57705/1639_F9_2_blue_red_green.jpg
    Figure 3 IF staining of human cell line SK-MEL-30
    Figure 3 IF staining of human cell line SK-MEL-30
    (Immunofluorescent staining of human cell line SK-MEL-30 shows localization to plasma membrane, cytosol & cytoplasmic bodies.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57705/1361_E6_2_blue_red_green.jpg
    Normal Tissue
    Figure 4 Colon
    Figure 4 Colon
    (Enterocytes - Microvilli
    Staining:High
    Intensity: Strong)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45339/162625_A_7_3.jpg
    Figure 5 Liver
    Figure 5 Liver
    (Hepatocytes
    Staining:High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45339/162625_A_8_4.jpg
    Figure 6 Kidney
    Figure 6 Kidney
    (Collecting ducts
    Staining:High
    Intensity: Strong
    Quantity: 75%-25%
    Distal tubules
    Staining:Medium
    Intensity: Strong
    Quantity: <25%
    Proximal tubules (microvilli)
    Staining:High
    Intensity: Strong)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45339/162625_A_9_5.jpg
    Figure 7 Testis
    Figure 7 Testis
    (Leydig cells
    Staining:High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45339/162625_A_4_6.jpg
    RNA Expression
    Figure 8 RNA cell line category: Group enriched (HSkMC, T-47d)
    Figure 8 RNA cell line category: Group enriched (HSkMC, T-47d)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000112964-GHR

    Specifications

    • Immunogen
    • hGHR/Fc
    • Host Species
    • Mouse
    • Specificity
    • Human
    • Species Reactivity
    • Human, Cynomolgus monkey
    • Clone
    • Ab13
    • Applications
    • Used for immunoassay techniques such as: Enzyme-linked Immunosorbent Assay; Flow Cytometry
    • Related Disease
    • Arthritis

    Target

    • Alternative Names
    • GHR; growth hormone receptor; GHBP; GH receptor; serum binding protein; somatotropin receptor; growth hormone binding protein

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

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    Select a product category from the dropdown menu below to view related products.
    Please select product type
    Single Domain Antibody Products IgG Antibody Products Mouse Antibody Products Humanized Antibody Products Neutralizing Antibody Products Rabbit Monoclonal Antibody Products Antibody Magnetic Beads Extracellular Vesicle (EV) Antibody Products
    CAT Product Name Application Type
    NAB-1090-VHH Recombinant Anti-Human GHR VHH Single Domain Antibody FA, FC, ICC, ELISA Llama VHH

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    For Research Use Only. Not For Clinical Use.

    For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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