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GPNMB
Loading...Anti-GPNMB Products
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- Derivation: Human
- Species Reactivity: Human
- Type: Human IgG2, κ
- Application: WB, IF, IP, Neut, FuncS, ELISA, FC
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- Derivation: Human
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Application: IF, IP, Neut, FuncS, ELISA
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- Human Anti-GPNMB Antibody, mRNA (TAB-330CL-mRNA)
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- Species Reactivity: Human
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- Human Anti-GPNMB Recombinant Antibody (HPAB-0006-LS) (HPAB-0006-LS)
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- Species Reactivity: Human
- Type: Human IgG2
- Application: ELISA, FC
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- Rabbit Anti-GPNMB Recombinant Antibody (HPAB-0005-LS) (HPAB-0005-LS)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, FC
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- Human Anti-GPNMB Recombinant Antibody (clone 1.7.1) (HPAB-1537-FY)
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- Species Reactivity: Human
- Type: Human IgG
- Application: Inhib, ELISA
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- Human Anti-GPNMB Recombinant Antibody (clone 1.2.2) (HPAB-1536-FY)
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- Species Reactivity: Human
- Type: Human IgG
- Application: Inhib, ELISA
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- Human Anti-GPNMB Recombinant Antibody (clone 1.10.2) (HPAB-1535-FY)
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- Species Reactivity: Human
- Type: Human IgG
- Application: Inhib, ELISA
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- Human Anti-GPNMB Recombinant Antibody (clone 1.2.2); scFv Fragment (HPAB-1536-FY-F(E))
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- Species Reactivity: Human
- Type: Human scFv
- Application: Inhib, ELISA
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- Human Anti-GPNMB Recombinant Antibody (clone 1.10.2); scFv Fragment (HPAB-1535-FY-F(E))
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- Species Reactivity: Human
- Type: Human scFv
- Application: Inhib, ELISA
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- Human Anti-GPNMB Recombinant Antibody scFv Fragment (HPAB-0006-LS-S(P)) (HPAB-0006-LS-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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- Rabbit Anti-GPNMB Recombinant Antibody; scFv Fragment (HPAB-0005-LS-S(P)) (HPAB-0005-LS-S(P))
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- Species Reactivity: Human
- Type: Rabbit scFv
- Application: FC
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- Human Anti-GPNMB Recombinant Antibody (clone 1.7.1); scFv Fragment (HPAB-1537-FY-F(E))
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- Species Reactivity: Human
- Type: Human scFv
- Application: Inhib, ELISA
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- Rabbit Anti-GPNMB Recombinant Antibody; Fab Fragment (HPAB-0005-LS-F(E)) (HPAB-0005-LS-F(E))
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- Species Reactivity: Human
- Type: Rabbit Fab
- Application: FC
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- Human Anti-GPNMB Recombinant Antibody Fab Fragment (HPAB-0006-LS-F(E)) (HPAB-0006-LS-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
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- Human Anti-GPNMB Recombinant Antibody (clone 1.7.1); Fab Fragment (HPAB-1537-FY-S(P))
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- Species Reactivity: Human
- Type: Human Fab
- Application: Inhib, ELISA
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- Human Anti-GPNMB Recombinant Antibody (clone 1.2.2); Fab Fragment (HPAB-1536-FY-S(P))
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- Species Reactivity: Human
- Type: Human Fab
- Application: Inhib, ELISA
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- Human Anti-GPNMB Recombinant Antibody (clone 1.10.2); Fab Fragment (HPAB-1535-FY-S(P))
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- Species Reactivity: Human
- Type: Human Fab
- Application: Inhib, ELISA
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- Recombinant Anti-Human GPNMB VHH Single Domain Antibody (NAB-1138-VHH)
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- Species Reactivity: Human
- Type: Llama VHH
- Application: WB, ICC, ChiP, FA, ELISA
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- Anti-Human GPNMB Recombinant Antibody (TAB-330CL)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Antibody
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- Species Reactivity: Human
- Target: GPNMB
- Host Animal: Human
- Application: ELISA, FC, Neut, Cell-uptake
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- Anti-Human GPNMB Immunohistochemistry Kit (VS-0525-XY2890)
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- Species Reactivity: Human
- Target: GPNMB
- Application: IHC
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- Anti-GPNMB Immunohistochemistry Kit (VS-0325-XY944)
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- Species Reactivity: Human
- Target: GPNMB
- Application: IHC
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- Human Anti-GPNMB scFv-Fc Chimera (VS-0425-FY114) (VS-0425-FY114)
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- Species Reactivity: Human
- Type: Human IgG2, scFv-Fc
- Application: ELISA, FC
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- Rabbit Anti-GPNMB Recombinant Antibody (VS13-YC462) (VS13-YC462)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IHC-P
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- Anti-GPNMB-vc-MMAE ADC (ADC-004LZY)
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- Target: GPNMB
- Linker: VC (Valine-citrulline)
- Drug: MMAE (monomethyl auristatin E)
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- Anti-GPNMB (CR011)-vcMMAE ADC (ADC-120LCT)
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- Target: glycoprotein NMB (GPNMB)
- Linker: VC (valine-citrulline)
- Drug: MMAE (Monomethyl auristatin E)
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For Research Use Only. Not For Clinical Use.
Background
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. GPNMB (Glycoprotein Nmb) is a Protein Coding gene. Diseases associated with GPNMB include Melanoma and Glioblastoma Multiforme. Among its related pathways are Signaling by GPCR and Signaling by PTK6. Gene Ontology (GO) annotations related to this gene include heparin binding and integrin binding. An important paralog of this gene is PMEL. Could be a melanogenic enzyme.
