Afuco™ Anti-Human IAPP ADCC Recombinant Antibody (NI-203), ADCC Enhanced
CAT#: AFC-360CL
Anti-IAPP ADCC Enhanced Antibody (NI-203) is an ADCC enhanced antibody produced by our Afuco™ platform. The antibodies specific for IAPP are used for the treatment and diagnosis of diseases from the group of Diabetes mellitus diseases, comprising type 1 diabetes (T1D), gestational diabetes, pre-diabetes, latent autoimmune diabetes of adults (LAD A; type 1, 5 diabetes) and/or type 2 diabetes (T2D).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53194/1947_F12_2_selected.jpg
Normal Tissue
Figure 2 High expression in pancreas
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53194/129355_A_1_3_val_selected.jpg
Normal Tissue
Figure 3 Low expression in colon
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53194/129355_A_9_3_val_selected.jpg
Normal Tissue
Figure 4 Pancreas
Pancreatic endocrine cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53194/129355_A_1_3.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (U-2 OS)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000121351-IAPP
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Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Diabetes
Product Property
- Purity
- >95% by HPLC
- Storage
- Store at –20 or -70°C upon receipt. Divide antibody into aliquots prior usage and avoid multiple freeze-thaw cycles.
Target
- Alternative Names
- IAPP; islet amyloid polypeptide; DAP; IAP; amylin; insulinoma amyloid peptide; diabetes-associated peptide; Islet amyloid polypeptide (diabetes-associated peptide; amylin)
- Gene ID
- 3375
- UniProt ID
- A0A024RAU1
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "IAPP"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2254z | Mouse Anti-IAPP Recombinant Antibody (clone 35D9) | ICC, IF, IHC | Mouse IgG1 |
| HPAB-0295-YC | Human Anti-IAPP Recombinant Antibody (clone HlLl) | FuncS | Humanized IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-375CL | Human Anti-IAPP Recombinant Antibody (TAB-375CL) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-118CT-S(P) | Human Anti-IAPP Recombinant Antibody; scFv Fragment (TAB-118CT-S(P)) | ELISA | Human scFv |
| TAB-119CT-S(P) | Human Anti-IAPP Recombinant Antibody; scFv Fragment (TAB-119CT-S(P)) | ELISA | Human scFv |
| TAB-120CT-S(P) | Human Anti-IAPP Recombinant Antibody; scFv Fragment (TAB-120CT-S(P)) | ELISA | Human scFv |
| TAB-118CT-F(E) | Human Anti-IAPP Recombinant Antibody; Fab Fragment (TAB-118CT-F(E)) | ELISA | Human Fab |
| TAB-119CT-F(E) | Human Anti-IAPP Recombinant Antibody; Fab Fragment (TAB-119CT-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC671 | PE-A*02:01/Human IAPP (KLQVFLIVL) MHC Tetramer | FCM | |
| MHC-LC672 | APC-A*02:01/Human IAPP (KLQVFLIVL) MHC Tetramer | FCM | |
| MHC-LC673 | BV421-A*02:01/Human IAPP (KLQVFLIVL) MHC Tetramer | FCM | |
| MHC-YF299 | A*02:01/Human IAPP (KLQVFLIVL) MHC Monomer | MHC Multimer |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0295-YC-S(P) | Human Anti-IAPP Recombinant Antibody (clone HlLl); scFv Fragment | FuncS | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0295-YC-F(E) | Human Anti-IAPP Recombinant Antibody (clone HlLl); Fab Fragment | FuncS | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3366 | Anti-IAPP Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0625-YC148 | Recombinant Anti-IAPP Eliminating Antibody, pH-Sensitive (VS-0625-YC148) | Antigen-Sweeping In Vivo. | Human IgG |
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