Afuco™ Anti-Human IL1RL1 ADCC Recombinant Antibody, ADCC Enhanced

Name: Afuco™ Anti-Human IL1RL1 ADCC Recombinant Antibody, ADCC Enhanced
SKU: AFC-394CL
Rating: 5 (1 reviews)

CAT#: AFC-394CL

Anti-IL1RL1 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. This is an antibody binding to IL33R has advantageous properties for the treatment of inflammatory diseases.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line U-2 OS

Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane, cytosol & focal adhesion sites.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7406/44_B9_1_selected.jpg

Normal Tissue Figure 2 IHC staining of human placenta

Immunohistochemical staining of human placenta shows membranous and cytoplasmic positivity in trophoblastic cells and stromal cells.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7406/ihc_selected.jpg

Normal Tissue Figure 3 IHC staining of human cerebral cortex

Immunohistochemical staining of human cerebral cortex shows strong cytoplasmic positivity in neuronal cells.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7917/ihc_selected.jpg

Normal Tissue Figure 5 Colon

Peripheral nerve/ganglion
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7406/23807_A_7_3.jpg

Normal Tissue Figure 6 Liver

Cholangiocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7406/23807_A_8_4.jpg

Normal Tissue Figure 7 Kidney

Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7406/23807_A_8_5.jpg

Normal Tissue Figure 8 Testis

Cells in seminiferous ducts
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7406/23807_A_6_6.jpg

Normal Tissue Figure 10 Lymph node

Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7406/23807_A_9_8.jpg

RNA Expression Figure 11 RNA cell line category: Group enriched (HHSteC, HMC-1, HUVEC TERT2)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000115602-IL1RL1

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Specifications

Host Species
Humanized

Derivation
Humanized

Type
ADCC enhanced antibody

Species Reactivity
Human

Related Disease
Inflammatory Diseases

Product Property

Purity
90–95% (SDS-PAGE)

Storage
Store at –20 or -70°C upon receipt. Divide antibody into aliquots prior usage and avoid multiple freeze-thaw cycles.

Target

Alternative Names
IL1RL1; interleukin 1 receptor-like 1; T1; ST2; DER4; ST2L; ST2V; FIT-1; IL33R; interleukin-1 receptor-like 1; growth stimulation-expressed; interleukin 1 receptor-related protein; homolog of mouse growth stimulation-expressed

Gene ID
9173

UniProt ID
Q01638

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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - AFC-394CL.pdf

MSDS

MSDS - AFC-394CL.pdf

COA

Certificate of Analysis Lookup

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