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ITGAX

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For Research Use Only. Not For Clinical Use.


Predicted to enable integrin binding activity and receptor tyrosine kinase binding activity. Involved in positive regulation of gene expression and positive regulation of myelination. Acts upstream of or within defense response to virus. Located in external side of plasma membrane. Is expressed in heart and hemolymphoid system. Orthologous to human ITGAX (integrin subunit alpha X).
Protein class

CD markers, FDA approved drug targets

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (Macrophages, Langerhans cells, granulocytes, NK-cells, Microglial cells, Kupffer cells, Alveolar cells type 2, Hofbauer cells)

Immune cell specificity

Immune cell enhanced (neutrophil)

Cell line specificity

Cell line enriched (HMC-1)

Interaction

Heterodimer of an alpha and a beta subunit. Alpha-X associates with beta-2.

Molecular function

Integrin, Receptor

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