LGALS1

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. This gene product may act as an autocrine negative growth factor that regulates cell proliferation. LGALS1 (Galectin 1) is a Protein Coding gene. Diseases associated with LGALS1 include Benign Metastasizing Leiomyoma and Thyroid Cancer. Among its related pathways are Apoptosis and Autophagy and MAP Kinase Signaling. Gene Ontology (GO) annotations related to this gene include obsolete signal transducer activity. An important paralog of this gene is LGALS2. Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis.