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RPS6KA1
Anti-RPS6KA1 Recombinant Antibody Products
- AbPlus™ Anti-RPS6KA1 Magnetic Beads (CBACN-658) (VS-0424-XY227)
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- Target: RPS6KA1
- Target Species: Human, Mouse, Rat
- Application: IP, Protein Purification
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- AbPlus™ Anti-RPS6KA1 Magnetic Beads (VS-0724-YC1347) (VS-0724-YC1347)
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- Target: RPS6KA1
- Target Species: Human, Mouse, Rat
- Application: IP, Protein Purification
Compare
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For Research Use Only. Not For Clinical Use.
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation.
Protein class
Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Proximal enterocytes, Distal enterocytes, NK-cells, monocytes)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (HMC-1, U-937)
Interaction
Forms a complex with either MAPK1/ERK2 or MAPK3/ERK1 in quiescent cells. Transiently dissociates following mitogenic stimulation. Interacts with ETV1/ER81 and FGFR1. (Microbial infection) Interacts with Kaposi's sarcoma-associated herpesvirus/HHV-8 protein ORF45; this interaction allows RPS6KA1 activation.
Molecular function
Kinase, Serine/threonine-protein kinase, Transferase
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