Anti-SOST Recombinant Antibody Products

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Anti-SOST Products

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For Research Use Only. Not For Clinical Use.

Creative Biolabs proudly offers a comprehensive portfolio of high-quality anti-SOST recombinant antibody products to support global researchers and biopharmaceutical companies. Our antibodies are meticulously designed and produced to meet the diverse needs of scientific investigations and therapeutic development in areas related to bone metabolism and beyond.

SOST: A Key Negative Regulator for Osteoporosis and Related Bone Metabolic Diseases

Sclerostin, expressed by the SOST gene, is a secreted glycoprotein generated largely by osteocytes. It acts as a negative regulator of bone production by blocking the Wnt/β-catenin signaling pathway. Research indicates that sclerostin plays a significant role in the pathogenesis of osteoporosis, particularly in cases associated with abnormal glucose metabolism, a condition increasingly prevalent worldwide. Given the rising global health concerns of both diabetes (affecting approximately 537 million individuals) and osteoporosis (affecting over 200 million), understanding the role of sclerostin is crucial for elucidating disease mechanisms and developing effective treatments.

Alternative Names

Sclerostin; CDD; SOST1; VBCH; DAND6; sclerostin.

Background

Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.

Anti-SOST rAb Products

Creative Biolabs' anti-SOST recombinant antibodies present notable advantages. Through advanced engineering, these antibodies exhibit enhanced specificity and affinity, thereby ensuring reliable and reproducible results. Recombinant technology also provides assurance of batch-to-batch consistency, which minimizes variability and enhances the accuracy of experimental and therapeutic applications. This level of precision is of significant importance in both research and clinical contexts.

Table 1. Featured anti-SOST recombinant antibody products at Creative Biolabs.

Creative Quality Control

Creative Biolabs maintains stringent quality control standards. Each anti-SOST recombinant antibody undergoes extensive analysis, including ELISA, Western blotting, immunohistochemistry, etc.. Antibody performance is validated in relevant applications, thereby ensuring optimal functionality and reliability. This dedication to quality assures that our goods satisfy the highest industry requirements.

Customer Reviews

Excellent

Sh***y
Human Anti-SOST Recombinant Antibody (HPAB-0342-YC) (CAT#: HPAB-0342-YC)

I've been using Creative Biolabs' anti-SOST antibody for my osteoporosis research, and the results are consistently excellent. The specificity is outstanding, and the data is highly reproducible. It's a game-changer for my experiments!

23/Apr/2023

Excellent

Ho***i
Mouse Anti-SOST Recombinant Antibody (HPAB-0343-YC) (CAT#: HPAB-0343-YC)

The customer service was incredibly helpful in selecting the right anti-SOST antibody for our project. The product arrived quickly, and the performance in our in vivo studies has been remarkable. We are quite pleased with our whole experience.

20/May/2024

Excellent

Ro***t
Human Anti-SOST Recombinant Antibody (HPAB-1123LY) (CAT#: HPAB-1123LY)

Creative Biolabs' anti-SOST antibody proved invaluable in our preclinical studies. Its consistent performance and high affinity significantly accelerated our timeline for evaluating novel therapeutic targets. We confidently endorse these antibodies for SOST-related investigations.

10/Nov/2024

rAb Production

Our anti-SOST recombinant antibodies are produced using state-of-the-art technology. We utilize advanced expression systems to ensure high yield and purity. This process guarantees a consistent supply of premium-quality antibodies, meeting the demands of both small-scale research and large-scale therapeutic development.

Featured Anti-SOST Recombinant Antibody Production Platforms
Fig.7 Milligram-scale anti-SOST recombinant antibody production.

Fig.8 Gram-scale anti-SOST recombinant antibody production.

rAb Modalities

Creative Biolabs offers a variety of anti-SOST recombinant antibody modalities to adapt to the various requirements of global customers.

Fig.9 Full-length anti-SOST recombinant antibody production and modalities.

SOST-Targeted Drug Information

Table 2. Public drug targeting SOST.

(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)

Creative Biolabs is committed to offering innovative solutions for your research and development requirements. To find out more about our goods and to discuss your specific requirements, please get in touch with us right away. Our anti-SOST recombinant antibodies exemplify our dedication to excellence, cutting-edge solutions, and ensuring customer satisfaction. Let us work with you to expedite scientific discoveries and therapeutic improvements.