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STAT5B

Anti-STAT5B Products

Recombinant Mouse anti-Human STAT5B Monoclonal antibody (EML1952) (MOB-1956CT)
- Species Reactivity: Human
- Application: WB
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Mouse Anti-STAT5B Recombinant Antibody (clone 42B11) (MOB-3860z)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, IP, IF, IHC, ELISA
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Mouse Anti-STAT5B Recombinant Antibody (clone 5B3) (VS3-XY1473)
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB
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Rabbit Anti-STAT5B Recombinant Antibody (VS3-CJ1022) (VS3-CJ1022)
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, ICC, IF, IHC, IP
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Mouse Anti-STAT5B Recombinant Antibody (ZG-117R) (ZG-117R)
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, ELISA
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Recombinant Rabbit Anti-STAT5B Monoclonal Antibody (CBACN-533) (MRO-1442-CN)
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC, IP
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Anti-STAT5B Immunohistochemistry Kit (VS-0525-XY6959)
- Species Reactivity: Human
- Target: STAT5B
- Application: IHC
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Hi-Affi™ Recombinant Rabbit Anti-STAT5B Monoclonal Antibody (TH258DS) (MOR-4744)
- Species Reactivity: Human, Mouse
- Type: IgG
- Application: WB, IF, ICC, IHC-P, FC, ChIP
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For Research Use Only. Not For Clinical Use.

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators.

Protein class

Cancer-related genes, Disease related genes, Human disease related genes, Transcription factors

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Late spermatids, Early spermatids)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (HDLM-2)

Interaction

Upon activation, forms homodimers (PubMed:29844444). Forms also heterodimers with related family members. Binds NR3C1 (By similarity). Interacts with NCOA1 (PubMed:12954634). Interacts with NMI (PubMed:9989503). Interacts with SOCS7 (PubMed:15677474). Interacts (via SH2 domain) with INSR (PubMed:9428692). Interacts with CPEB3; this inhibits STAT5B-mediated transcriptional activation (PubMed:20639532).

Molecular function

Activator, DNA-binding

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Related Diseases

Endometrial Cancer