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JAK3

The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction.
Protein class

Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (T-cells, B-cells, dendritic cells, NK-cells, Plasma cells, Macrophages)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (HDLM-2, HEL, HMC-1, Karpas-707, U-266/70, U-266/84, U-937)

Interaction

Interacts with STAM2 and MYO18A (By similarity). Interacts with SHB.

Molecular function

Kinase, Transferase, Tyrosine-protein kinase

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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