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10-FnIII anti-LYZ (SFN-L013)

The tenth fibronectin type III domain (10Fn3) that bound lysozyme was isolated from the library using mRNA Display technology. The fibronectin type III domain (FN3) is a small autonomous folding unit which occurs in many animal proteins involving in ligand binding. The β-sandwich structure of FN3 closely resembles that of immunoglobulin domains. After affinity maturation, 10Fn3 variants were identified having affinities (KD=0.35 nM) for lysozyme as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.      
Datasheet
Specifications
Scaffold Name
10-FnIII
Origin
Fibronectin
Core Structure
β-sandwich of 7 β-strands
Variable Regions
2–3 loops
Target
Lysozyme
Species Reactivity
Chicken
Expression Host
E. coli
Affinity Constant
0.35 nM
Applications
ELISA; immunohistochemistry; Microscopy; Flow Cytometer; Western Blotting; Functional Study
Target
Alternative Names
Fibronectin; 10-FnIII; LYZC
Entrez Gene ID
396218
UniProt ID
P00698

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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Recombinant Humanized Anti-Chicken LYZ Antibody scFv Fragment (HuLys11)    ( PSBW-023 )
Recombinant Mouse Anti-Chicken LYZ Antibody scFv Fragment (D44.1)    ( PSBZ-022 )
Recombinant Anti-Chicken LYZ VHH Single Domain Antibody ()    ( PNBL-024 )
Recombinant Mouse Anti-Turkey LYZ Antibody (HyHEL-10 (SFSF)    ( PABC-129 )
Recombinant Human Anti-Lysozyme Antibody Fab Fragment (HYHEL-10)    ( PFBL-267 )
Recombinant Anti-Human LYZ VHH Single Domain Antibody (cAbHuL5)    ( PNBL-023 )
Recombinant Mouse Anti-Chicken LYZ (D18A) Antibody Fab Fragment (D1.3)    ( PFBZ-025 )
>> MORE
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