Recombinant Anti-human Aβ42 Intrabody [(D-Arg)9]
CAT#: IAB-B042(A)
Recombinant anti-Aβ42 intrabody linked to (D-Arg)9 works within cells and binds specifically to intracellur Aβ42, expressed in E. coli cells. The intrabodies, one with an endoplasmic reticulum (ER) targeting signal and one devoid of a targeting sequence, were assessed in cells harboring a doxycycline (Dox)-regulated mutant human amyloid precursor protein Swedish mutant (hAPPswe) transcription unit for their abilities to prevent Aβ peptide egress.
Specifications
- Immunogen
- human Amyloid β Peptide 42
- Host Species
- human
- Type
- scFv-(D-Arg)9
- Cell Penetrating Peptide
- (D-Arg)9
It has been proven that polyarginine peptides composed of nine arginine amino acids (Arg-9) are able to translocate across cells very efficiently. This raises the question if molecular dynamics simulations would show a similar pathway for this highly hydrophilic and charged peptide as predicted for the Tat peptide. The simplicity of Arg-9 over other CPPs also helps isolate the role of the Arg sidechain on the translocation without the effect of other sidechains. Therefore, in this work we study computationally the translocation of Arg-9 through a lipid bilayer and show that the translocation mechanism is the same as for the Tat peptide.
- Species Reactivity
- human
- Applications
- Used for immunoassay techniques such as: Coimmunopricipation; Functional studies
Product Property
- Purity
- >95%, by SDS-PAGE with Coomassie Brilliant Blue staining
- Storage
- Short Term Storage: 4°C
Long Term Storage: -20°C
Target
- Alternative Names
- Aβ42; Amyloid β Peptide 42
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for IAB-B042(A). Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Aβ42"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-25 | Recombinant Anti-human Aβ42 Antibody | WB, FC, FuncS | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-25-F(E) | Recombinant Anti-human Aβ42 Antibody Fab Fragment | Neut, IF, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-25-S(P) | Recombinant Anti-human Aβ42 Antibody scFv Fragment | WB, FC, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B042(G) | Recombinant Anti-human Aβ42 Intrabody [+36 GFP] | ELISA, IF, Neut, FuncS | scFv-(+36GFP) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B042(T) | Recombinant Anti-human Aβ42 Intrabody [Tat] | ELISA, Neut, FuncS | scFv-Tat |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-25 | Recombinant Human Anti-human Aβ42 Antibody | FC, WB, FuncS | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-25-F(E) | Recombinant Human Anti-human Aβ42 Antibody Fab Fragment | IF, FC, Biosensors, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-25-S(P) | Recombinant Human Anti-human Aβ42 Antibody scFv Fragment | Neut, WB, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0160-CN | Human Anti-Aβ42 Recombinant Antibody (clone scFv59) | WB, ELISA, IF, IHC | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0160-CN-S(P) | Human Anti-Aβ42 Recombinant Antibody (clone scFv59); scFv Fragment | WB, ELISA, IF, IHC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0160-CN-F(E) | Human Anti-Aβ42 Recombinant Antibody (clone scFv59); Fab Fragment | WB, ELISA, IF, IHC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0511-WJ | Mouse Anti-Aβ42 Recombinant Antibody (clone 3F5) | Inhib, ELISA, Live cell imaging, FuncS | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0511-WJ-F(E) | Mouse Anti-Aβ42 Recombinant Antibody (clone 3F5); Fab Fragment | ELISA, FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0511-WJ-S(P) | Mouse Anti-Aβ42 Recombinant Antibody (clone 3F5); scFv Fragment | ELISA, FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0586-FY | Human Anti-Aβ42 Recombinant Antibody (clone M06) | DB, ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0586-FY-S(P) | Human Anti-Aβ42 Recombinant Antibody (clone M06); scFv Fragment | DB, ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0586-FY-F(E) | Human Anti-Aβ42 Recombinant Antibody (clone M06); Fab Fragment | DB, ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2023-FY-VHH | Camelid Anti-Aβ42 Recombinant Single Domain Antibody (HPAB-2023-FY-VHH) | ELISA | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2024-FY-VHH | Camelid Anti-Aβ42 Recombinant Single Domain Antibody (HPAB-2024-FY-VHH) | ELISA | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2025-FY-VHH | Camelid Anti-Aβ42 Recombinant Single Domain Antibody (HPAB-2025-FY-VHH) | ELISA | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY167 | Human Anti-Aβ42 (clone 8F5) scFv-Fc Chimera | Neut, ELISA, DB | Human IgG1, scFv-Fc |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: WB, FC, IP, ELISA, Neut, FuncS, IF
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: ELISA, Neut, IF, IP, FC, FuncS
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: ELISA, IP, FC, FuncS, Neut, IF, IHC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: WB, FC, IP, ELISA, Neut, FuncS, IF
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: WB, ELISA, FuncS
Application: FuncS, Inhib, IP, ELISA
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
