Recombinant Anti-human Aβ42 Intrabody [+36 GFP]
CAT#: IAB-B042(G)
Recombinant anti-Aβ42 intrabody in fusion with +36GFP works within cells to bind intracellur Aβ42, expressed in E. coli cells. The intrabodies, one with an endoplasmic reticulum (ER) targeting signal and one devoid of a targeting sequence, were assessed in cells harboring a doxycycline (Dox)-regulated mutant human amyloid precursor protein Swedish mutant (hAPPswe) transcription unit for their abilities to prevent Aβ peptide egress.
Specifications
- Immunogen
- human Amyloid β Peptide 42
- Host Species
- human
- Type
- scFv-(+36GFP)
- Cell Penetrating Peptide
- +36 GFP
GFP with a theoretical net charge of +36 (+36 GFP) penetrated several different mammalian cell lines at very low (nanomolar) concentrations. Cationic peptides and proteins have been observed to penetrate cells, and both natural and synthetic cell-penetrating peptides are widely used as delivery vehicles. However, whereas a covalent link between the cell-penetrating peptide and its cargo is typically required.
- Species Reactivity
- human
- Applications
- Products can be used for: Enzyme-linked Immunosorbent Assay; Immunofluorescence; Neutralization; Functional studies
Product Property
- Purity
- >95% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE
- Storage
- ≤1 year at -20°C.
Target
- Alternative Names
- Aβ42; Amyloid β Peptide 42
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
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| MOB-25 | Recombinant Anti-human Aβ42 Antibody | WB, FC, FuncS | IgG |
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| MOB-25-S(P) | Recombinant Anti-human Aβ42 Antibody scFv Fragment | WB, FC, FuncS | scFv |
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| HPAB-0586-FY-S(P) | Human Anti-Aβ42 Recombinant Antibody (clone M06); scFv Fragment | DB, ELISA | Human scFv |
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| CAT | Product Name | Application | Type |
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| HPAB-2023-FY-VHH | Camelid Anti-Aβ42 Recombinant Single Domain Antibody (HPAB-2023-FY-VHH) | ELISA | Llama VHH |
| HPAB-2024-FY-VHH | Camelid Anti-Aβ42 Recombinant Single Domain Antibody (HPAB-2024-FY-VHH) | ELISA | Llama VHH |
| HPAB-2025-FY-VHH | Camelid Anti-Aβ42 Recombinant Single Domain Antibody (HPAB-2025-FY-VHH) | ELISA | Llama VHH |
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| VS-0325-FY167 | Human Anti-Aβ42 (clone 8F5) scFv-Fc Chimera | Neut, ELISA, DB | Human IgG1, scFv-Fc |
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