Recombinant Mouse Antibody (A20) is capable of binding to AAV VP1 , expressed in Chinese Hamster Ovary cells (CHO). A20 is a monoclonal antibody which neutralizes AAV-2 and AAV-3B subsequent to primary receptor binding.
Figure 1 Time course of AAV infection using A20 immunocytochemistry.
HeLa cells were infected with wild-type AAV at a MOI of 10,000 particles per cell for 10 min at 37°C, washed to remove unadsorbed virus, and incubated at 37°C. Viral particles were detected with A20 monoclonal antibody.
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