Human Anti-ACVR2B Recombinant Antibody Fab Fragment (TAB-0662CLV-F(E))

Name: Human Anti-ACVR2B Recombinant Antibody Fab Fragment (TAB-0662CLV-F(E))
SKU: TAB-0662CLV-F(E)
Rating: 5 (1 reviews)

CAT#: TAB-0662CLV-F(E)

The anti-ActRIIB antibody specifically bind to ActRIIB, also known as ACVR2B. The specific antibody can be used in the treatment of musculoskeletal disease, Parkinson's Diseases and so on.

Gene Expression

Subcellular Location and Protein Expression Figure 1 IF staining of cell line A-431

Immunofluorescent staining of cell line A-431 shows localization to cytosol.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/115/672_E2_1_blue_red_green.jpg

Subcellular Location and Protein Expression Figure 2 IF staining of cell line U-2 OS

Immunofluorescent staining of cell line U-2 OS shows localization to cytosol.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/115/663_E2_1_blue_red_green.jpg

Subcellular Location and Protein Expression Figure 3 IF staining of cell line U-251 MG

Immunofluorescent staining of cell line U-251 MG shows localization to cytosol.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/115/646_E2_1_blue_red_green.jpg

Normal Tissue Figure 4 Colon

Endocrine cells
Staining:High
Intensity: Strong
Enterocytes
Staining:Medium
Intensity: Strong
Quantity: <25%

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3804/10580_A_9_3.jpg

Normal Tissue Figure 5 Kidney

Cells in tubules
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3804/10580_A_9_5.jpg

Normal Tissue Figure 6 Testis

Pachytene spermatocytes
Staining:High
Intensity: Strong
Quantity: 75%-25% Spermatogonia cells
Staining:Medium
Intensity: Strong
Quantity: <25%

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3804/10580_A_4_6.jpg

Normal Tissue Figure 7 Placenta

Decidual cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Trophoblastic cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3804/10580_A_2_7.jpg

Normal Tissue Figure 8 Lymph node

Germinal center cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3804/10580_A_8_8.jpg

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Specifications

Immunogen
Human ActRIIB ECD, ActRIIB-Fc (for library screening)

Host Species
Human

Type
Human antibody

Specificity
Human

Related Disease
Musculoskeletal disease, Parkinson's Disease,

Target

Alternative Names
ACVR2B; activin A receptor, type IIB; HTX4; ACTRIIB; ActR-II

Gene ID
93

UniProt ID
Q13705

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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - TAB-0662CLV-F(E).pdf

MSDS

MSDS - TAB-0662CLV-F(E).pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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NAB-50-sdAb	Recombinant Anti-Human ACVR2B VHH Single Domain Antibody	WB, IP, ChiP, Neut, ELISA	Llama VHH

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TAB-012CL	Human Anti-ACVR2B Recombinant Antibody (TAB-012CL)	ELISA	Human IgG

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MOR-0064	Hi-Affi™ Rabbit Anti-ACVR2B Recombinant Antibody (clone DS64AB)	WB	Rabbit IgG

CAT	Product Name	Application	Type
HPAB-0038-FY	Human Anti-ACVR2B Recombinant Antibody (HPAB-0038-FY)	ELISA, FC, Inhib, FuncS	Human IgG2
HPAB-N0010-YC	Human Anti-ACVR2B Recombinant Antibody (HPAB-N0010-YC)	FC	Human IgG
ZG-0132U	Rabbit Anti-ACVR2B Recombinant Antibody (clone 7B10)	ELISA, IHC	Rabbit IgG
VS3-FY1964	Rabbit Anti-ACVR2B Recombinant Antibody (clone R01-2I1)	WB	Rabbit IgG
VS-0824-YJ24	Human Anti-ACVR2B Recombinant Antibody (clone CBA103)	IA	Human IgG1 kappa

CAT	Product Name	Application	Type
HPAB-0038-FY-S(P)	Human Anti-ACVR2B Recombinant Antibody; scFv Fragment (HPAB-0038-FY-S(P))	ELISA	Human scFv
HPAB-N0010-YC-S(P)	Human Anti-ACVR2B Recombinant Antibody scFv Fragment (HPAB-N0010-YC-S(P))	FC	Human scFv
HPAB-0575-WJ-S(P)	Human Anti-ACVR2B Recombinant Antibody; scFv Fragment (HPAB-0575-WJ-S(P))	ELISA	Human scFv
HPAB-0576-WJ-S(P)	Human Anti-ACVR2B Recombinant Antibody; scFv Fragment (HPAB-0576-WJ-S(P))	ELISA	Human scFv
HPAB-0577-WJ-S(P)	Human Anti-ACVR2B Recombinant Antibody; scFv Fragment (HPAB-0577-WJ-S(P))	ELISA	Human scFv

CAT	Product Name	Application	Type
HPAB-N0010-YC-F(E)	Human Anti-ACVR2B Recombinant Antibody Fab Fragment (HPAB-N0010-YC-F(E))	FC	Human Fab
HPAB-0575-WJ-F(E)	Human Anti-ACVR2B Recombinant Antibody; Fab Fragment (HPAB-0575-WJ-F(E))	ELISA	Human Fab
HPAB-0576-WJ-F(E)	Human Anti-ACVR2B Recombinant Antibody; Fab Fragment (HPAB-0576-WJ-F(E))	ELISA	Human Fab
HPAB-0577-WJ-F(E)	Human Anti-ACVR2B Recombinant Antibody; Fab Fragment (HPAB-0577-WJ-F(E))	ELISA	Human Fab
HPAB-0578-WJ-F(E)	Human Anti-ACVR2B Recombinant Antibody; Fab Fragment (HPAB-0578-WJ-F(E))	ELISA	Human Fab

CAT	Product Name	Application	Type
VS-0425-FY31	Human Anti-ACVR2B scFv-Fc Chimera (VS-0425-FY31)	IA	Human IgG1, scFv-Fc

CAT	Product Name	Application	Type
VS-0425-YC316	Recombinant Anti-ACVR2B Vesicular Antibody, EV Displayed (VS-0425-YC316)	ELISA, FC, Cell-uptake

CAT	Product Name	Application	Type
VS-0525-XY140	Anti-ACVR2B Immunohistochemistry Kit	IHC

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