Anti-Human AGER Recombinant Antibody (CAT#: TAB-025CL)
Recombinant Humanized monoclonal antibody expressed in CHO binding to Human AGER. These antibodiess have the ability to inhibit the binding of RAGE to its various ligands. The antibodiess or portions thereof of described in the present application are useful for treating a disease or disorder characterized by or induced by pathophysiological ligands of RAGE, for example missfolded proteins like amyloid β and advanced glycation-end-products.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line MCF7
(Immunofluorescent staining of human cell line MCF7 shows localization to nucleoli fibrillar center & cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/64436/1232_G12_3_selected.jpg
(Immunofluorescent staining of human cell line MCF7 shows localization to nucleoli fibrillar center & cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/64436/1232_G12_3_selected.jpg
Figure 2 Lung
(Alveolar cells type I
Staining: High
Intensity: Strong
Quantity:>75%
Alveolar cells type II
Staining: Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69474/168057_A_2_4.jpg
(Alveolar cells type I
Staining: High
Intensity: Strong
Quantity:>75%
Alveolar cells type II
Staining: Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69474/168057_A_2_4.jpg
Figure 3 RNA cell line category: Cell line enhanced (HEK93, JURKAT, RPTEC TERT1, U-266/70, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000204305-AGER
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000204305-AGER
Specifications
- Derivation
- Humanized
- Type
- Antibody
- Species Reactivity
- Human
- Related Disease
- Inflammatory Diseases
Product Property
- Purity
- >95% by HPLC
- Storage
- Short Term Storage: 4°C
Long Term Storage: -20°C
Target
- Alternative Names
- AGER; advanced glycosylation end product-specific receptor; RAGE; RAGE isoform sRAGE-delta; RAGE isoform NtRAGE-delta; receptor for advanced glycation end-products variant 20
- Gene ID
- 177
- UniProt ID
- B4DNX3
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibodies
Fab Antibodies
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Mouse Antibodies
Neutralizing Antibodies
Blocking Antibodies
Rabbit Monoclonal Antibodies
IHC Kits & Antibodies
FC Reagents & Kits
Extracellular Vesicle Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-44 | Recombinant Anti-human AGER Antibody | WB, FC, FuncS | IgG |
| MHH-44 | Recombinant Human Anti-human AGER Antibody | ELISA, WB, IP, FuncS | IgG |
| HPAB-0086-YC | Mouse Anti-AGER Recombinant Antibody (HPAB-0086-YC) | ELISA, RIA, IHC, Neut | Mouse IgG |
| VS3-WK1912 | Recombinant Rabbit Anti-Rat AGER Capture Antibody (clone R45-9J-5) | ELISA | Rabbit IgG |
| VS3-WK1913 | Recombinant Rabbit Anti-Rat AGER Detection Antibody (clone R87-7G-5) | ELISA | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
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