Afuco™ Anti-Human C3 ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-078CL)
Anti-C3 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. This is an anti-C3b antibody containing various combinations of complementarity determining regions 1 through 3 (CDRs 1 through 3), and framework regions (FR1 through FR4). The the framework regions are used for the treatment of disease conditions for which alternative complement pathway plays a role.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Normal Tissue
RNA Expression
Figure 1 Kidney
(Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Proximal tubules (cell body)
Staining: Medium
Intensity: Moderate
Quantity:>75%
Proximal tubules (microvilli)
Staining: Medium
Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3563/10702_A_9_5.jpg
(Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Proximal tubules (cell body)
Staining: Medium
Intensity: Moderate
Quantity:>75%
Proximal tubules (microvilli)
Staining: Medium
Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3563/10702_A_9_5.jpg
Figure 2 RNA cell line category: Group enriched (BJ hTERT+, EFO-21, Hep G2, HSkMC, SiHa)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000125730-C3
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000125730-C3
Specifications
- Host Species
- Humanized
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Complement-associated Disorder
Product Property
- Purity
- >95% as judged by SDS-polyacrylamide gel electrophoresis
- Storage
- ≤6 months at 4°C; ≥6 months at -20°C.
Target
- Alternative Names
- C3; complement component 3; ASP; C3a; C3b; AHUS5; ARMD9; CPAMD1; HEL-S-62p; complement C3; prepro-C3; C3a anaphylatoxin; complement component C3; complement component C3a; complement component C3b; acylation-stimulating protein cleavage product; epididymis secretory sperm binding protein Li 62p; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1
- Gene ID
- 718
- UniProt ID
- P01024
Related Resources
Systemic Lupus Erythematosus
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IHC Kits & Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-142 | Recombinant Human Anti-human C3 Antibody | ELISA, WB, IP, FuncS | IgG |
| MRO-0205-CN | Mouse Anti-C3 Recombinant Antibody (clone 6-A10) | WB, IHC, ELISA | Mouse IgG1 |
| MRO-0378-CN | Mouse Anti-C3 Recombinant Antibody (clone 11-10) | WB, IF, FC | Mouse IgG2b |
| ZG-0302U | Rabbit Anti-C3 Recombinant Antibody (clone E28-P) | IHC-P | Rabbit IgG |
| VS3-FY175 | Recombinant Rabbit Anti-C3 Antibody (clone R06-2C2) | WB, IHC-P | Rabbit IgG |
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