Afuco™ Anti-Human C3 ADCC Recombinant Antibody, ADCC Enhanced
CAT#: AFC-078CL
Anti-C3 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. This is an anti-C3b antibody containing various combinations of complementarity determining regions 1 through 3 (CDRs 1 through 3), and framework regions (FR1 through FR4). The the framework regions are used for the treatment of disease conditions for which alternative complement pathway plays a role.
Gene Expression
Normal Tissue
Figure 1 Kidney
Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Proximal tubules (cell body)
Staining: Medium
Intensity: Moderate
Quantity:>75%
Proximal tubules (microvilli)
Staining: Medium
Intensity: Moderate
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3563/10702_A_9_5.jpg
RNA Expression
Figure 2 RNA cell line category: Group enriched (BJ hTERT+, EFO-21, Hep G2, HSkMC, SiHa)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000125730-C3
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Specifications
- Host Species
- Humanized
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Complement-associated Disorder
Product Property
- Purity
- >95% as judged by SDS-polyacrylamide gel electrophoresis
- Storage
- ≤6 months at 4°C; ≥6 months at -20°C.
Target
- Alternative Names
- C3; complement component 3; ASP; C3a; C3b; AHUS5; ARMD9; CPAMD1; HEL-S-62p; complement C3; prepro-C3; C3a anaphylatoxin; complement component C3; complement component C3a; complement component C3b; acylation-stimulating protein cleavage product; epididymis secretory sperm binding protein Li 62p; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1
- Gene ID
- 718
- UniProt ID
- P01024
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Related Diseases
Systemic Lupus Erythematosus
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-142-F(E) | Recombinant Anti-human C3 Antibody Fab Fragment | ELISA, RIA, FuncS | Fab |
| HPAB-0182-YC-F(E) | Human Anti-C3 Recombinant Antibody; Fab Fragment (HPAB-0182-YC-F(E)) | Neut | Humanized Fab |
| FAMAB-0160JF-F(E) | Rabbit Anti-C3 Recombinant Antibody (clone BA8); Fab Fragment | IHC, ELISA, FuncS | Rabbit Fab |
| FAMAB-0161JF-F(E) | Rabbit Anti-C3 Recombinant Antibody (clone MA11); Fab Fragment | IHC, ELISA, FuncS | Rabbit Fab |
| FAMAB-0162JF-F(E) | Rabbit Anti-C3 Recombinant Antibody (clone KG3); Fab Fragment | IHC, ELISA, FuncS | Rabbit Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-142-S(P) | Recombinant Anti-human C3 Antibody scFv Fragment | FC, RIA, Biosensors, FuncS | scFv |
| HPAB-0939LY-S(P) | Human Anti-C3 Recombinant Antibody (clone SS3-4); scfv Fragment | ELISA | Humanized scfv |
| FAMAB-0160JF-S(P) | Rabbit Anti-C3 Recombinant Antibody (clone BA8); scFv Fragment | IHC, ELISA, FuncS | Rabbit scFv |
| FAMAB-0161JF-S(P) | Rabbit Anti-C3 Recombinant Antibody (clone MA11); scFv Fragment | IHC, ELISA, FuncS | Rabbit scFv |
| FAMAB-0162JF-S(P) | Rabbit Anti-C3 Recombinant Antibody (clone KG3); scFv Fragment | IHC, ELISA, FuncS | Rabbit scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-080CQ | Mouse Anti-C3 Recombinant Antibody (clone K13/16) | ELISA, IP, WB, Neut | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0414 | Hi-Affi™ Rabbit Anti-C3 Recombinant Antibody (clone DS414AB) | IHC-P, IHC-Fr | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABC-558 | Recombinant Llama Anti-C3 Single Domain Antibody (PABC-558) | ELISA, Inhib | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY284 | Anti-C3 Immunohistochemistry Kit | IHC | |
| VS-0525-XY880 | Anti-Mouse C3 Immunohistochemistry Kit | IHC | |
| VS-0525-XY879 | Anti-Human C3 Immunohistochemistry Kit | IHC |
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|---|---|---|---|
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