Mouse Anti-CCR2 Recombinant Antibody (clone 1D9); Fab Fragment (CAT#: HPAB-0251-YC-F(E))
CCR2, which is a receptor for the C-C chemokines can bind MCP-1, MCP-2, MCP-3, MCP-4 and MCP-5. CCR2 as well as processes and cellular responses mediated by CCR2, are involved in rejection of transplanted grafts.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line THP-1
(Immunofluorescent staining of human cell line THP-1 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/63255/1926_C6_4_selected.jpg
(Immunofluorescent staining of human cell line THP-1 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/63255/1926_C6_4_selected.jpg
Figure 2 IHC staining of human cervix, uterine
(Immunohistochemical staining of human cervix, uterine shows strong cytoplasmic positivity in squamous epithelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3793/ihc_selected.jpg
(Immunohistochemical staining of human cervix, uterine shows strong cytoplasmic positivity in squamous epithelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3793/ihc_selected.jpg
Figure 3 Cervix
(Squamous epithelial cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3793/10521_B_8_3.jpg
(Squamous epithelial cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3793/10521_B_8_3.jpg
Figure 4 Lymph node
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3793/10521_A_9_8.jpg
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3793/10521_A_9_8.jpg
Figure 5 RNA cell line category: Cell line enhanced (Karpas-707, THP-1, U-266/70, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000121807-CCR2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000121807-CCR2
Specifications
- Host Species
- Mouse
- Type
- Mouse Fab
- Specificity
- Human CCR2
- Species Reactivity
- Human
- Clone
- 1D9
- Applications
- Antagonist
- Related Disease
- Immunosuppressive
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Chemokine (C-C Motif) Receptor 2; Monocyte Chemoattractant Protein 1 Receptor; CC-CKR-2; MCP-1-R; CMKBR2; CCR-2; Monocyte Chemotactic Protein 1 Receptor; MCP-1 Receptor; CD192 Antigen; C-C CKR-2; CCR2A; CCR2B; CD192; CKR2A; CKR2B; CKR2
- Gene ID
- 729230
- UniProt ID
- P41597
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-159 | Recombinant Anti-human CCR2 Antibody | WB, IF, FuncS | IgG |
| HPAB-0247-YC | Human Anti-CCR2 Recombinant Antibody (HPAB-0247-YC) | ELISA, FC | Human IgG4 |
| HPAB-0248-YC | Human Anti-CCR2 Recombinant Antibody (HPAB-0248-YC) | ELISA, FC | Human IgG4 |
| HPAB-0249-YC | Human Anti-CCR2 Recombinant Antibody (HPAB-0249-YC) | ELISA, FC | Human IgG4 |
| HPAB-0250-YC | Human Anti-CCR2 Recombinant Antibody (HPAB-0250-YC) | ELISA, FC | Human IgG4 |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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