Human Anti-CCR2 Recombinant Antibody (clone h1D9); scFv Fragment (CAT#: HPAB-0252-YC-S(P))
Provided is humanized antibody that binds to huamn CCR2, and the antibody can be as an effective antagonist of CCR2 function.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line THP-1
(Immunofluorescent staining of human cell line THP-1 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/63255/1926_C6_4_selected.jpg
(Immunofluorescent staining of human cell line THP-1 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/63255/1926_C6_4_selected.jpg
Figure 2 IHC staining of human cervix, uterine
(Immunohistochemical staining of human cervix, uterine shows strong cytoplasmic positivity in squamous epithelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3793/ihc_selected.jpg
(Immunohistochemical staining of human cervix, uterine shows strong cytoplasmic positivity in squamous epithelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3793/ihc_selected.jpg
Figure 3 Cervix
(Squamous epithelial cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3793/10521_B_8_3.jpg
(Squamous epithelial cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3793/10521_B_8_3.jpg
Figure 4 Lymph node
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3793/10521_A_9_8.jpg
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3793/10521_A_9_8.jpg
Figure 5 RNA cell line category: Cell line enhanced (Karpas-707, THP-1, U-266/70, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000121807-CCR2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000121807-CCR2
Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized scFv
- Specificity
- Human CCR2
- Species Reactivity
- Human
- Clone
- h1D9
- Applications
- Antagonist
- Related Disease
- Immunosuppressive
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Chemokine (C-C Motif) Receptor 2; Monocyte Chemoattractant Protein 1 Receptor; CC-CKR-2; MCP-1-R; CMKBR2; CCR-2; Monocyte Chemotactic Protein 1 Receptor; MCP-1 Receptor; CD192 Antigen; C-C CKR-2; CCR2A; CCR2B; CD192; CKR2A; CKR2B; CKR2
- Gene ID
- 729230
- UniProt ID
- P41597
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IHC Kits & Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-159-F(E) | Recombinant Anti-human CCR2 Antibody Fab Fragment | FC, ELISA, FuncS | Fab |
| MHH-159-F(E) | Recombinant Human Anti-human CCR2 Antibody Fab Fragment | FC, WB, FuncS | Fab |
| HPAB-0247-YC-F(E) | Human Anti-CCR2 Recombinant Antibody; Fab Fragment (HPAB-0247-YC-F(E)) | ELISA, FC | Human Fab |
| HPAB-0248-YC-F(E) | Human Anti-CCR2 Recombinant Antibody; Fab Fragment (HPAB-0248-YC-F(E)) | ELISA, FC | Human Fab |
| HPAB-1571WJ-F(E) | Human Anti-CCR2 Recombinant Antibody; Fab Fragment (clone hu1D9) | ELISA, WB | Human Fab |
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