Afuco™ Anti-Human CLEC12A ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-161CL)
Anti-CLEC12A ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. This is an antibodiy that specifically bind to human CLL-1, in particular to the extracellular domain of a CLL-1 expressing cell. The CLL-1 antibodies can inhibit cancer cell growth (proliferation and/or engraftment) and thus can be considered chemotherapeutic agents alone.
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Normal Tissue
RNA Expression
Figure 1 Colon
(Glandular cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48515/114818_A_7_3.jpg
(Glandular cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48515/114818_A_7_3.jpg
Figure 2 Kidney
(Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48515/114818_A_7_5.jpg
(Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48515/114818_A_7_5.jpg
Figure 3 High expression in bone marrow
(Hematopoietic cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48515/114818_B_5_4.jpg
(Hematopoietic cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48515/114818_B_5_4.jpg
Figure 4 RNA cell line category: Group enriched (HL-60, U-937)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000172322-CLEC12A
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000172322-CLEC12A
Specifications
- Host Species
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Hematologic malignancies
Product Property
- Purity
- >97%, by SDS-PAGE under reducing conditions
- Storage
- Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Target
- Alternative Names
- CLEC12A; C-type lectin domain family 12, member A; CLL1; MICL; CLL-1; DCAL-2; C-type lectin domain family 12 member A; C-type lectin protein CLL-1; C-type lectin-like molecule-1; dendritic cell-associated lectin 2; myeloid inhibitory C-type lectin-like receptor
- Gene ID
- 160364
- UniProt ID
- Q5QGZ9
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| MOB-1855z | Mouse Anti-CLEC12A Recombinant Antibody (clone 31C4) | FC | Mouse IgG2b |
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| HPAB-2073LY | Mouse Anti-CLEC12A Recombinant Antibody (HPAB-2073LY) | ELISA, FC | Mouse IgG |
| HPAB-2074LY | Human Anti-CLEC12A Recombinant Antibody (HPAB-2074LY) | ELISA, FC | Human IgG |
| HPAB-2075LY | Mouse Anti-CLEC12A Recombinant Antibody (HPAB-2075LY) | ELISA, FC | Mouse IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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