Afuco™ Anti-Human CLEC12A ADCC Recombinant Antibody, ADCC Enhanced
CAT#: AFC-161CL
Anti-CLEC12A ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. This is an antibodiy that specifically bind to human CLL-1, in particular to the extracellular domain of a CLL-1 expressing cell. The CLL-1 antibodies can inhibit cancer cell growth (proliferation and/or engraftment) and thus can be considered chemotherapeutic agents alone.
Gene Expression
Normal Tissue
Figure 1 Colon
Glandular cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/48515/114818_A_7_3.jpg
Normal Tissue
Figure 2 Kidney
Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/48515/114818_A_7_5.jpg
Normal Tissue
Figure 3 High expression in bone marrow
Hematopoietic cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/48515/114818_B_5_4.jpg
RNA Expression
Figure 4 RNA cell line category: Group enriched (HL-60, U-937)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000172322-CLEC12A
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Specifications
- Host Species
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Hematologic malignancies
Product Property
- Purity
- >97%, by SDS-PAGE under reducing conditions
- Storage
- Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Target
- Alternative Names
- CLEC12A; C-type lectin domain family 12, member A; CLL1; MICL; CLL-1; DCAL-2; C-type lectin domain family 12 member A; C-type lectin protein CLL-1; C-type lectin-like molecule-1; dendritic cell-associated lectin 2; myeloid inhibitory C-type lectin-like receptor
- Gene ID
- 160364
- UniProt ID
- Q5QGZ9
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1855z | Mouse Anti-CLEC12A Recombinant Antibody (clone 31C4) | FC | Mouse IgG2b |
| HPAB-2073LY | Mouse Anti-CLEC12A Recombinant Antibody (HPAB-2073LY) | ELISA, FC | Mouse IgG |
| HPAB-2074LY | Human Anti-CLEC12A Recombinant Antibody (HPAB-2074LY) | ELISA, FC | Human IgG |
| HPAB-2075LY | Mouse Anti-CLEC12A Recombinant Antibody (HPAB-2075LY) | ELISA, FC | Mouse IgG |
| HPAB-2076LY | Mouse Anti-CLEC12A Recombinant Antibody (HPAB-2076LY) | ELISA, FC | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-511LC | Mouse Anti-CLEC12A Recombinant Antibody (TAB-511LC) | FuncS | Mouse IgG |
| TAB-515LC | Mouse Anti-CLEC12A Recombinant Antibody (TAB-515LC) | Cyt, FuncS, Inhib | Mouse IgG2b |
| TAB-516LC | Mouse Anti-CLEC12A Recombinant Antibody (TAB-516LC) | Cyt, FuncS, Inhib | Mouse IgG2b |
| TAB-517LC | Mouse Anti-CLEC12A Recombinant Antibody (TAB-517LC) | Cyt, FuncS | Mouse IgG1 |
| TAB-518LC | Mouse Anti-CLEC12A Recombinant Antibody (TAB-518LC) | CDC | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-512LC | Human Anti-CLEC12A Recombinant Antibody (TAB-512LC) | FuncS | Chimeric (mouse/human) IgG |
| TAB-512LC-F(E) | Human Anti-CLEC12A Recombinant Antibody; Fab Fragment (TAB-512LC-F(E)) | ELISA | Chimeric (mouse/human) Fab |
| TAB-523LC-F(E) | Human Anti-CLEC12A Recombinant Antibody; Fab Fragment (TAB-523LC-F(E)) | ELISA | Chimeric antibody (mouse/human) |
| TAB-524LC-F(E) | Human Anti-CLEC12A Recombinant Antibody; Fab Fragment (TAB-524LC-F(E)) | ELISA | Chimeric antibody (mouse/human) |
| TAB-525LC-F(E) | Human Anti-CLEC12A Recombinant Antibody; Fab Fragment (TAB-525LC-F(E)) | ELISA | Chimeric antibody (mouse/human) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-513LC | Human Anti-CLEC12A Recombinant Antibody (TAB-513LC) | FuncS | Humanized IgG |
| TAB-514LC | Human Anti-CLEC12A Recombinant Antibody (TAB-514LC) | FuncS | Humanized IgG |
| TAB-513LC-S(P) | Human Anti-CLEC12A Recombinant Antibody; scFv Fragment (TAB-513LC-S(P)) | ELISA | Humanized scFv |
| TAB-513LC-F(E) | Human Anti-CLEC12A Recombinant Antibody; Fab Fragment (TAB-513LC-F(E)) | ELISA | Humanized Fab |
| TAB-514LC-F(E) | Human Anti-CLEC12A Recombinant Antibody; Fab Fragment (TAB-514LC-F(E)) | ELISA | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2073LY-F(E) | Mouse Anti-CLEC12A Recombinant Antibody; Fab Fragment (HPAB-2073LY-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-2074LY-F(E) | Human Anti-CLEC12A Recombinant Antibody; Fab Fragment (HPAB-2074LY-F(E)) | ELISA, FC | Human Fab |
| HPAB-2075LY-F(E) | Mouse Anti-CLEC12A Recombinant Antibody; Fab Fragment (HPAB-2075LY-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-0259-WJ-F(E) | Human Anti-CLEC12A Recombinant Antibody; Fab Fragment (HPAB-0259-WJ-F(E)) | ELISA | Humanized Fab |
| HPAB-1076-FY-S(P) | Mouse Anti-CLEC12A Recombinant Antibody; scFv Fragment (HPAB-1076-FY-S(P)) | Activ | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2073LY-S(P) | Mouse Anti-CLEC12A Recombinant Antibody; scFv Fragment (HPAB-2073LY-S(P)) | ELISA, FC | Mouse scFv |
| HPAB-2074LY-S(P) | Human Anti-CLEC12A Recombinant Antibody; scFv Fragment (HPAB-2074LY-S(P)) | ELISA, FC | Human scFv |
| HPAB-2075LY-S(P) | Mouse Anti-CLEC12A Recombinant Antibody; scFv Fragment (HPAB-2075LY-S(P)) | ELISA, FC | Mouse scFv |
| HPAB-2076LY-S(P) | Mouse Anti-CLEC12A Recombinant Antibody; scFv Fragment (HPAB-2076LY-S(P)) | ELISA, FC | Mouse scFv |
| HPAB-0259-WJ-S(P) | Human Anti-CLEC12A Recombinant Antibody; scFv Fragment (HPAB-0259-WJ-S(P)) | ELISA | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0924-YC125 | Mouse Anti-CLEC12A Recombinant Antibody Hexamer (VS-0924-YC125), CDC Enhanced | CDC | Antibody hexamer |
| VS-0924-YC126 | Human Anti-CLEC12A Recombinant Antibody Hexamer (VS-0924-YC126), CDC Enhanced | ELISA, CDC | Antibody hexamer |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY84 | CytoStream™ Mouse Anti-CLEC12A Recombinant Antibody (clone 50C1) | FC | Mouse IgG2a, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY10 | Human Anti-CLEC12A scFv-Fc Chimera (VS-0325-FY10) | ELISA, FC | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY467 | Anti-CLEC12A Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC129 | Recombinant Anti-CLEC12A Vesicular Antibody, EV Displayed (VS-0425-YC129) | ELISA, FC, Cell-uptake |
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