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    Anti-Human DSG1 Recombinant Antibody (CAT#: TAB-220CL)

    Recombinant Humanized monoclonal antibody expressed in CHO binding to Human DSG1. This is an anti-Dsg1 mAbs useful for studying Dsg1 function and mechanisms of blister formation in PF and for developing targeted therapies and tools to monitor disease activity. Pemphigus foliaceus (PF) is a blistering disease caused by autoantibodiess to desmoglein 1 (Dsg1) that cause loss of epidermal cell adhesion.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
    Quantity :
    Conjugation :
    Fc Engineering :
    Modalities :
    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Normal Tissue
    Figure 1 Skin
    Figure 1 Skin
    (Cells in basal layer
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Cells in corneal layer
    Staining:High
    Intensity: Strong
    Quantity: 75%-25%
    Cells in granular layer
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Cells in spinous layer
    Staining:High
    Intensity: Strong
    Quantity:>75%
    Langerhans cells
    Staining:High
    Intensity: Strong
    Quantity:>75%)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/22128/169913_B_8_1.jpg
    RNA Expression
    Figure 2 RNA cell line category: Cell line enriched (hTCEpi)
    Figure 2 RNA cell line category: Cell line enriched (hTCEpi)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000134760-DSG1

    Specifications

    • Derivation
    • Humanized
    • Type
    • Antibody
    • Species Reactivity
    • Human
    • Related Disease
    • Pemphigus foliaceus

    Product Property

    • Purity
    • >90% assessed by SDS-PAGE
    • Storage
    • Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.

    Target

    • Alternative Names
    • DSG1; desmoglein 1; DG1; DSG; CDHF4; EPKHE; PPKS1; SPPK1; EPKHIA; desmoglein-1; DGI; cadherin family member 4; desmosomal glycoprotein 1; pemphigus foliaceus antigen

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "DSG1"

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    CAT Product Name Application Type
    NAB-786-sdAb Recombinant Anti-Human DSG1 VHH Single Domain Antibody IP, ChiP, IHC, ELISA Llama VHH

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    For Research Use Only. Not For Clinical Use.

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