Afuco™ Anti-Human FGFR1 ADCC Recombinant Antibody (OM-RCA-01), ADCC Enhanced
CAT#: AFC-270CL
Anti-FGFR1 ADCC Enhanced Antibody (OM-RCA-01) is an ADCC enhanced antibody produced by our Afuco™ platform. OM-RCA-01 is a novel humanized monoclonal antibody targeting fibroblast growth factor receptor 1, used for treatment of metastatic renal cell carcinoma (RCC).
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/33614/67230_B_9_5.jpg
Normal Tissue
Figure 2 Colon
Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/33614/67230_A_9_3.jpg
Normal Tissue
Figure 3 Kidney
Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/33614/67230_A_8_5.jpg
Normal Tissue
Figure 4 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/33614/67230_A_6_6.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (AN3-CA, BJ hTERT+)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000077782-FGFR1
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Specifications
- Host Species
- Humanized
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Renal Cell Carcinoma
Product Property
- Purity
- >97%, by SDS-PAGE under reducing conditions
- Storage
- Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Target
- Alternative Names
- FGFR1; fibroblast growth factor receptor 1; CEK; FLG; HH2; OGD; FLT2; KAL2; BFGFR; CD331; FGFBR; FLT-2; HBGFR; N-SAM; FGFR-1; HRTFDS; bFGF-R-1; FGFR1/PLAG1 fusion; proto-oncogene c-Fgr; FMS-like tyrosine kinase 2; hydroxyaryl-protein kinase; fms-related tyrosine kinase 2; heparin-binding growth factor receptor; basic fibroblast growth factor receptor 1
- Gene ID
- 2260
- UniProt ID
- P11362
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Related Diseases
EGFR Tyrosine Kinase Inhibitor Resistance
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1638z | Mouse Anti-FGFR1 Recombinant Antibody (clone 20H8) | WB, ELISA, FC, ICC, IF, IHC | Mouse IgG2b |
| MOB-0108MZ | Recombinant Mouse Anti-Human FGFR1 Antibody (clone N6G11) | WB, IP, IHC | Mouse antibody |
| HPAB-0485LY | Human Anti-FGFR1 Recombinant Antibody (clone 121-R3P1-A7/C6/D9) | ELISA | Human IgG |
| HPAB-0486LY | Human Anti-FGFR1 Recombinant Antibody (clone 121-R3P1-A9/H10) | ELISA | Human IgG |
| HPAB-0701-FY | Human Anti-FGFR1 Recombinant Antibody (HPAB-0701-FY) | ELISA | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-283CL | Human Anti-FGFR1 Recombinant Antibody (TAB-283CL) | WB, IHC | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-052WM | Anti-Human FGFR1 Recombinant Antibody (FR1-H7) | ELISA, Neut | Human Antibody |
| TAB-054WM | Human Anti-FGFR1 Recombinant Antibody (TAB-054WM) | ELISA | Human IgG |
| TAB-052WM-S(P) | Anti-Human FGFR1 Recombinant Antibody scFv Fragment (FR1-H7) | ELISA, BL, Neut | Human Antibody |
| TAB-054WM-S(P) | Human Anti-FGFR1 Recombinant Antibody; scFv Fragment (TAB-054WM-S(P)) | ELISA | Human scFv |
| TAB-052WM-F(E) | Anti-Human FGFR1 Recombinant Antibody Fab Fragment (FR1-H7) | ELISA, BL, Neut | Human Antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-053WM | Mouse Anti-FGFR1 Recombinant Antibody (TAB-053WM) | WB, FC | Mouse IgG |
| TAB-053WM-S(P) | Mouse Anti-FGFR1 Recombinant Antibody; scFv Fragment (TAB-053WM-S(P)) | WB | Mouse scFv |
| TAB-053WM-F(E) | Mouse Anti-FGFR1 Recombinant Antibody; Fab Fragment (TAB-053WM-F(E)) | WB | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-825CQ | Mouse Anti-FGFR1 Recombinant Antibody (clone CBL537) | WB, Neut | Mouse IgG1 |
| NEUT-826CQ | Mouse Anti-FGFR1 Recombinant Antibody (clone MM0277-6F10) | WB, Neut | Mouse IgG1 |
| NEUT-827CQ | Mouse Anti-FGFR1 Recombinant Antibody (clone CBL059) | Neut, WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1296 | Hi-Affi™ Rabbit Anti-FGFR1 Recombinant Antibody (clone DS1296AB) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0118-FY-S(P) | Human Anti-FGFR1 Recombinant Antibody; scFv Fragment (HPAB-0118-FY-S(P)) | ELISA | Human scFv |
| HPAB-N0346-YC-S(P) | Human Anti-FGFR1 Recombinant Antibody scFv Fragment (HPAB-N0346-YC-S(P)) | ELISA, FuncS | Human scFv |
| HPAB-0485LY-S(P) | Human Anti-FGFR1 Recombinant Antibody (clone 121-R3P1-A7/C6/D9); scFv Fragment | ELISA | Human scFv |
| HPAB-0701-FY-F(E) | Human Anti-FGFR1 Recombinant Antibody Fab Fragment (HPAB-0701-FY-F(E)) | ELISA | Human Fab |
| HPAB-3044LY-S(P) | Mouse Anti-FGFR1 Recombinant Antibody; scFv Fragment (HPAB-3044LY-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0118-FY-F(E) | Human Anti-FGFR1 Recombinant Antibody; Fab Fragment (HPAB-0118-FY-F(E)) | ELISA | Human Fab |
| HPAB-N0346-YC-F(E) | Human Anti-FGFR1 Recombinant Antibody Fab Fragment (HPAB-N0346-YC-F(E)) | ELISA, FuncS | Human Fab |
| HPAB-0485LY-F(E) | Human Anti-FGFR1 Recombinant Antibody (clone 121-R3P1-A7/C6/D9); Fab Fragment | ELISA | Human Fab |
| HPAB-0486LY-F(E) | Human Anti-FGFR1 Recombinant Antibody (clone 121-R3P1-A9/H10); Fab Fragment | ELISA | Human Fab |
| HPAB-3044LY-F(E) | Mouse Anti-FGFR1 Recombinant Antibody; Fab Fragment (HPAB-3044LY-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0125-FY35 | Human Anti-FGFR1 (clone FR1-H7) scFv-Fc Chimera | ELISA, Neut | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC333 | Recombinant Anti-FGFR1 Vesicular Antibody, EV Displayed (VS-0425-YC333) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2538 | Anti-FGFR1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2539 | Anti-Mouse FGFR1 Immunohistochemistry Kit | IHC |
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