Anti-Human GDF15 Recombinant Antibody (3C7-3-1) (CAT#: TAB-1282CL)
This is an anti-BMP9 monoclonal antibody that bonds to human BMP9 (bone morphogenetic protein-9), which can be used as a medicinal composition for use in treating ectopic ossification disease.
Specific Inquiry
ELISA
Figure 1 is a diagram shows the binding of the obtained anti-human BMP9 monoclonal antibody to human BMP9 by ELISA.
The horizontal axis represents antibody concentration (ng / mL), and the vertical axis represents absorbance (450-570 nm) at each antibody concentration. In each case, no antibody is indicated by ○, 3B7-3-3 antibody is indicated by Δ, 3C7-3-1 antibody is indicated by □, and R D antibody is indicated by ●.
Inhib
Figure 2 shows the inhibitory action of the obtained anti-human BMP9 monoclonal antibody on the binding of human BMP9 and labeled R & D antibody.
The horizontal axis represents the concentration of unlabeled antibody (ng / mL), and the vertical axis represents the inhibitory activity (%) of each antibody against the binding of BMP9 / R D antibody. The 3B7-3-3 antibody is indicated by Δ, the 3C7-3-1 antibody is indicated by □, and the R D antibody is indicated by ●.
FuncS
Figure 3 is a graph shows the effect of an anti-human BMP9 monoclonal antibody on bone differentiation (increased alkaline phosphatase activity) of a FOP-ALK2 gene-introduced C2C12 cell line by adding a human BMP9 recombinant protein.
The horizontal axis represents the antibody concentration (ng / mL), and the vertical axis represents the inhibitory activity (%) of each antibody against bone differentiation caused by the addition of the BMP9 recombinant protein. The 3C7-3-1 antibody is indicated by Δ, and the R D antibody is indicated by ●.
Specifications
- Immunogen
- Human BMP9 recombinant protein
- Host Species
- Mouse
- Specificity
- Human
- Clone
- 3C7-3-1
- Applications
- ELISA, FuncS, Inhib
- Related Disease
- Ectopic ossification disease
Applications
- Application Notes
- This antibody has been reported for use in Enzyme-linked Immunosorbent Assay, Functional Assay, Inhibition.
Target
- Alternative Names
- GDF2; growth differentiation factor 2; BMP9; HHT5; BMP-9
- Gene ID
- 2658
- UniProt ID
- Q9UK05
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Rabbit Monoclonal Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-391 | Recombinant Anti-human GDF15 Antibody | ELISA, WB, IF, FuncS | IgG |
| MHH-391 | Recombinant Human Anti-human GDF15 Antibody | ELISA, WB, FuncS | IgG |
| MOB-0141CT | Recombinant Mouse anti-Human GDF15 Monoclonal antibody (NN0408-20B4) | FC, WB | |
| HPAB-M0522-YC | Human Anti-GDF15 Recombinant Antibody (HPAB-M0522-YC) | ELISA, Block | Human IgG |
| HPAB-M0523-YC | Human Anti-GDF15 Recombinant Antibody (HPAB-M0523-YC) | ELISA, Block | Human IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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