Recombinant Anti-human GLI3 Intrabody [(D-Arg)₉] (CAT#: IAB-B069(A))

• Immunogen
• human GLI family zinc finger 3

• Host Species
• llama

• Type
• vhh-(D-Arg)₉

• Cell Penetrating Peptide
• (D-Arg)₉
  It has been proven that polyarginine peptides composed of nine arginine amino acids (Arg-9) are able to translocate across cells very efficiently. This raises the question if molecular dynamics simulations would show a similar pathway for this highly hydrophilic and charged peptide as predicted for the Tat peptide. The simplicity of Arg-9 over other CPPs also helps isolate the role of the Arg sidechain on the translocation without the effect of other sidechains. Therefore, in this work we study computationally the translocation of Arg-9 through a lipid bilayer and show that the translocation mechanism is the same as for the Tat peptide.

• Species Reactivity
• human

• Applications
• Formats of immunological tests: Immunofluorescence; Flow Cytometry; Western blot; Functional studies

• Purity
• >95%, by SDS-PAGE with Coomassie Brilliant Blue staining

• Storage
• Store at -20°C for long-term storage. Store at 4°C for up to one month. Avoid freeze/thaw cycles.

• Alternative Names
• GLI3; GLI family zinc finger 3; PHS; ACLS; GCPS; PAPA; PAPB; PAP-A; PAPA1; PPDIV; GLI3FL; GLI3-190; transcriptional activator GLI3; oncogene GLI3; zinc finger protein GLI3; GLI-Kruppel family member GLI3; glioma-associated oncogene family zinc finger 3

• Gene ID
• 2737

• UniProt ID
• P10071

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