The antibody (clone HA-20) is a recombinant mouse antibody targeting HBEGF. HA-20 can inhibit the growth of RMG-1 cells in an antibody concentration-dependent manner. It has potential uses in the studies of pancreatic cancer, liver cancer, esophageal cancer, melanoma, and other cancers.
Figure 1 The binding activity of antibodies HA-20, HB-20, and HC-15 to active-form HB-EGF;
Figure 2 Histograms that show the binding activity of antibodies HA-20, HB-20, and HC-15 to proHB-EGF.
Figure 3 The inhibition of binding of HB-EGF to EGFR by antibodies HA-20, HB-20, and HC-15.
Figure 4 Compares the inhibition of the growth of EGFR_Ba/F3 cells by antibodies HA-20, HB-20, and HC-15.
Figure 5 The inhibition of growth of the ovarian cancer cell line RMG-1 by the antibodies HA-20, HB-20, and HC-15 in a medium containing 8% FCS;
Figure 6 The internalization-mediated activity of the HA-20, HB-20, and HC-15 antibodies to induce cell death in SKOV-3 cells (original cell line) and HB-EGF_SKOV3 cells (high HB-EGF-expressing SKOV-3 cells).
Figure 7 The binding activity of the HA-20, HB-20, and HC-15 antibodies for the HB-EGF on ES-2 cells.
Figure 8 The internalization-mediated cell death inducing activity of HA-20, HB-20, and HC-15, on ES-2 ovarian cancer cells.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1493z | Mouse Anti-HBEGF Recombinant Antibody (clone 25C6) | WB, IHC, Neut | Mouse IgG1 |
MOB-2309MZ | Recombinant Mouse Anti-Human HBEGF Antibody (clone 5H20), Biotin-Conjugated | ICC/IF, IP, WB | Mouse antibody |
HPAB-0593-CN | Human Anti-HBEGF Recombinant Antibody (HPAB-0593-CN) | WB, ELISA, FC, Neut | Chimeric (mouse/human) IgG1 |
VS-0723-WK72 | Human Anti-HBEGF Recombinant Antibody (VS-0723-WK72) | FC | Chimeric (rabbit/human) IgG1 |
VS-0224-XY84 | Rat Anti-Mouse Hbegf Recombinant Antibody (VS-0224-XY84) | ELISA | Rat IgG2a |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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