Mouse Anti-HBEGF Recombinant Antibody (clone HB-20) (CAT#: HPAB-0092-LS)
The antibody is used for the treatment of pancreatic cancer, liver cancer, esophageal cancer, melanomacancpreferabal.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
ELISA
Figure 1 The binding activity of antibodies HA-20, HB-20, and HC-15 to active-form HB-EGF;
FC
Figure 2 Histograms that show the binding activity of antibodies HA-20, HB-20, and HC-15 to proHB-EGF.
Inhib
Figure 3 The inhibition of binding of HB-EGF to EGFR by antibodies HA-20, HB-20, and HC-15.
Inhib
Figure 4 Compares the inhibition of the growth of EGFR_Ba/F3 cells by antibodies HA-20, HB-20, and HC-15.
FuncS
Figure 5 The inhibition of growth of the ovarian cancer cell line RMG-1 by the antibodies HA-20, HB-20, and HC-15 in a medium containing 8% FCS;
FuncS
Figure 6 The internalization-mediated activity of the HA-20, HB-20, and HC-15 antibodies to induce cell death in SKOV-3 cells (original cell line) and HB-EGF_SKOV3 cells (high HB-EGF-expressing SKOV-3 cells).
FC
Figure 7 The binding activity of the HA-20, HB-20, and HC-15 antibodies for the HB-EGF on ES-2 cells.
FuncS
Figure 8 The internalization-mediated cell death inducing activity of HA-20, HB-20, and HC-15, on ES-2 ovarian cancer cells.
FC
Figure 9 The FACS analysis of the binding activity exhibited by various anti-HB-EGF antibodies for HB-EGF overexpressed in Ba/F3 cells; the fluorescence intensity is expressed on the vertical axis as the G-mean value.
ADCC
Figure 10 The ADCC activity exhibited by various anti-HB-EGF antibodies on HB-EGF_Ba/F3 cells (upper) and the CDC activity exhibited by various anti-HB-EGF antibodies on HB-EGF_Ba/F3 cells (lower); the vertical axis shows the amount of chromium released from the cells due to ADCC-mediated or CDC-mediated cytotoxicity.
Specifications
- Immunogen
- HBEGF
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human HBEGF
- Species Reactivity
- Human
- Clone
- HB-20
- Applications
- Inhib, FC, ELISA, ADCC, FuncS
- Related Disease
- Pancreatic cancer, liver cancer, esophageal cancer, melanoma
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Inhibition, Flow Cytometry, Enzyme-linked Immunosorbent Assay, ADCC, Functional Assay.
Target
Related Resources
Bladder Cancer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Humanized Antibody Products
Mouse Antibody Products
Neutralizing Antibody Products
IgG Antibody Products
ScFv Antibody Products
Fab Antibody Products
Single Domain Antibody Products
Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-340CL | Anti-Human HBEGF Recombinant Antibody (KHK2866) | FuncS | Antibody |
| TAB-015CT | Anti-Human HB-EGF Recombinant Antibody | ELISA, Inhibition, FC | Humanized antibody |
| TAB-015CT-S(P) | Anti-Human HB-EGF Recombinant Antibody scFv Fragment | ELISA, Inhibition, FC | Humanized antibody |
| TAB-015CT-F(E) | Anti-Human HB-EGF Recombinant Antibody Fab Fragment | ELISA, Inhibition, FC | Humanized antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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