Anti-HCV E2 Recombinant Antibody (e20) (CAT#: MRO-1202LC)
This product is a recombinant human anti-Hepatitis C virus monoclonal antibody. e20 specifically binds to glycoprotein E2 associated with HCV and can be potentially used in the treatment and diagnosis of Hepatitis C virus infection.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Neut
Figure 1 Neutralizing activity of Fab e20 using virus pseudoparticles (HCVpp).
The following strains were used: genotype 1a UKN1A20.8. Data obtained from HCVpp infection in the presence of different concentrations of c33-3 (negative control) and e20 are presented as a percentage of the infection detected in the absence of antibody. The means and standard errors of two replicate assays are reported.
Hepatitis C Virus (HCV) Infection May Elicit Neutralizing Antibodies Targeting Epitopes Conserved in All Viral Genotypes
Neut
Figure 2 Neutralizing activity of Fab e20 using the HCVcc system (genotype 2a).
The infectivity of JFH-1 in the presence of e20 and of negative-control Fab (c33-3) is presented as the viral RNA quantity normalized against glyceraldehyde-3-phosphate dehydrogenase RNA, as determined by quantitative reverse transcription-PCR. The means and standard errors of three replicate assays are reported.
Hepatitis C Virus (HCV) Infection May Elicit Neutralizing Antibodies Targeting Epitopes Conserved in All Viral Genotypes
Inhib
Figure 3 Inhibition of binding of probe FLAG-Fab antigen by previous binding of different concentrations of purified unlabeled Fabs used as competitors.
Mapping B-Cell Epitopes of Hepatitis C Virus E2 Glycoprotein Using Human Monoclonal Antibodies from Phage Display Libraries
Inhib
Figure 4 Inhibition of binding of human recombinant Fabs by previous binding of a 1:20 dilution of sera obtained from HCV-infected patients and from two HCV-negative controls.
All HCV-positive sera were demonstrated to contain HCV RNA of genotype 1b and to have an ELISA titer against HCV/E2 of>1:500.
Specifications
- Host Species
- Human
- Type
- Human antibody
- Specificity
- Hepatitis C virus
- Clone
- e20
- Applications
- ELISA, Neut
- Related Disease
- Hepatitis C virus infection
Applications
- Application Notes
- The HCV E2 Protein antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Neutralization.
Target
- Alternative Names
- Hepatitis C virus; HCV; HCV E2; Hepatitis C virus E2
- Gene ID
- 951475
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| DrMAB-938 | Recombinant Human Anti-HCV E2 Antibody scFv Fragment | ELISA, IHC | scFv |
| MOB-446-S(P) | Recombinant Anti-HCV E2 Antibody scFv Fragment | ELISA, IP, FuncS | scFv |
| HPAB-0005-WJ-S(P) | Recombinant Human Anti-HCV E2 Antibody scFv Fragment (HC-84.1) | ELISA, Neut | Human scFv |
| HPAB-0050-WJ-S(P) | Mouse Anti-HCV E2 Protein Recombinant Antibody; scFv Fragment (HPAB-0050-WJ-S(P)) | ELISA | Mouse scFv |
| PSBC-319 | Recombinant Mouse Anti-HCV E2 Antibody scFv Fragment (DAO5) | ELISA, FC | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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