Anti-HIV-1 gp41 Recombinant Antibody scFv Fragment (4E10-IgG3) (CAT#: MRO-025LC-S(P))
This product is a scfv format of recombinant human anti-HIV-1 gp41 monoclonal antibody. 4E10-IgG3 specifically binds to gp41 and can be potentially used in the studies of acquired immunodeficiency syndrome (AIDS), a condition in humans characterized by clinical features including wasting syndromes, central nervous system degeneration and profound immunosuppression that results in life-threatening opportunistic infections and malignancies. The 4E10 epitope on gp41 is represented as a pink helix parallel to the plane of the viral membrane and the epitope seems to be exposed and susceptible to antibody binding and virus neutralization in the metastable and receptor-bound states of gp41.
Specific Inquiry
Specifications
- Host Species
- Human
- Type
- Human antibody
- Specificity
- HIV-1
- Clone
- 4E10-IgG3
- Related Disease
- AIDS
Target
- Alternative Names
- Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP41; gp41; HIV envelope
- Gene ID
- 155971
- UniProt ID
- P04578
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
Fab Antibody Products
Human Antibody Products
MHC Tetramer Products for Virology
IgM Antibody Products
ScFv Antibody Products
ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-486 | Recombinant Anti-HIV-1 gp41 Antibody | WB, Dot, FuncS | IgG |
| PABL-558 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 8066) | WB, Neut | Human IgG |
| PABL-559 | Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone 11f10) | WB, ELISA, FuncS | Mouse IgG |
| PABL-560 | Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone 6a7) | WB, ELISA, FuncS | Mouse IgG |
| PABL-561 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone mAb1281) | ELISA, Neut | Human IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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