Human Anti-HLA-DRB1 Recombinant Antibody (clone HD8); scFv Fragment
CAT#: HPAB-0026-YC-S(P)
The anti-HLA-DR antibody that recognizes the human leucocyte antigen-DR (HLA-DR), which is a cell membrane molecule associated with immunity. And anti-HLA-DR antibody can be as a preventive or therapeutic agent for immune responses caused by an HLA-DR-expressing cell, especially, a therapeutic agent for chronic rheumatism.
Gene Expression
Normal Tissue
Figure 1 Lymph node
Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/15400/34565_A_8_8.jpg
Normal Tissue
Figure 2 Tonsil
Germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/15400/34565_A_4_8.jpg
RNA Expression
Figure 3 RNA cell line category: Cell line enhanced (HDLM-2, HMC-1, THP-1, U-266/70, U-698, U-87 MG)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000196126-HLA-DRB1
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Specifications
- Host Species
- Human
- Type
- Human scFv
- Specificity
- Human HLA-DRB1
- Species Reactivity
- Human, Mouse
- Clone
- HD8
- Applications
- Cyt, WB
- Related Disease
- Malignant tumor, Chronic rheumatism
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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|---|---|---|---|
| MOB-1090z-F(E) | Recombinant Anti-Human HLA-DRB1 Antibody Fab Fragment | Neut, IF, FuncS | Fab |
| HPAB-0023-YC-F(E) | Human Anti-HLA-DRB1 Recombinant Antibody (clone huA33); Fab Fragment | ELISA | Humanized Fab |
| HPAB-0024-YC-F(E) | Human Anti-HLA-DRB1 Recombinant Antibody (clone de-immunized huA33); Fab Fragment | ELISA | Humanized Fab |
| HPAB-0025-YC-F(E) | Human Anti-HLA-DRB1 Recombinant Antibody (clone HD4); Fab Fragment | Cyt, WB | Human Fab |
| HPAB-0086-FY-F(E) | Mouse Anti-HLA-DRB1 Recombinant Antibody; Fab Fragment (HPAB-0086-FY-F(E)) | WB | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1090z-S(P) | Recombinant Anti-Human HLA-DRB1 Antibody scFv Fragment | WB, FC, FuncS | scFv |
| HPAB-0023-YC-S(P) | Human Anti-HLA-DRB1 Recombinant Antibody (clone huA33); scFv Fragment | ELISA | Humanized scFv |
| HPAB-0024-YC-S(P) | Human Anti-HLA-DRB1 Recombinant Antibody (clone de-immunized huA33); scFv Fragment | ELISA | Humanized scFv |
| HPAB-0025-YC-S(P) | Human Anti-HLA-DRB1 Recombinant Antibody (clone HD4); scFv Fragment | Cyt, WB | Human scFv |
| HPAB-0086-FY-S(P) | Mouse Anti-HLA-DRB1 Recombinant Antibody; scFv Fragment (HPAB-0086-FY-S(P)) | WB | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-150 | Anti-Human HLA DR beta Recombinant Antibody (Apolizumab) | ELISA, IP, FC, FuncS, Neut, IF, ICC | IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1623 | Rabbit Anti-HLA-DRB1 Recombinant Antibody (clone DS1623AB) | WB, IHC, ICC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0023-YC | Human Anti-HLA-DRB1 Recombinant Antibody (clone huA33) | ELISA | Humanized IgG |
| HPAB-0024-YC | Human Anti-HLA-DRB1 Recombinant Antibody (clone de-immunized huA33) | ELISA | Humanized IgG |
| HPAB-0025-YC | Human Anti-HLA-DRB1 Recombinant Antibody (clone HD4) | Cyt, WB | Human IgG |
| HPAB-0026-YC | Human Anti-HLA-DRB1 Recombinant Antibody (clone HD8) | Cyt, WB | Human IgG |
| HPAB-0086-FY | Mouse Anti-HLA-DRB1 Recombinant Antibody (HPAB-0086-FY) | FC, WB, EM, Cyt | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-150 | Afuco™ Anti-HLA-DRB1 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-150) | ELISA, IP, FC, FuncS, Neut, IF | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY251 | Mouse Anti-NHP HLA-DRB1 Recombinant Antibody (clone LN-3) | WB, IF, FC | Mouse IgG2b, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1029 | Anti-HLA-DRB1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3182 | Anti-Mouse HLA-DRB1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3183 | Anti-Porcine HLA-DRB1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3185 | Anti-Human HLA-DRB1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC242 | Recombinant Anti-HLA-DRB1 Vesicular Antibody, EV Displayed (VS-0425-YC242) | ELISA, FC, Neut, Cell-uptake |
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