Anti-Human HLA DR beta Recombinant Antibody (Apolizumab)
CAT#: TAB-150
Recombinant monoclonal antibody to HLA DR beta.
Gene Expression
Normal Tissue
Figure 1 Lymph node
Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/15400/34565_A_8_8.jpg
Normal Tissue
Figure 2 Tonsil
Germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/15400/34565_A_4_8.jpg
RNA Expression
Figure 3 RNA cell line category: Cell line enhanced (HDLM-2, HMC-1, THP-1, U-266/70, U-698, U-87 MG)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000196126-HLA-DRB1
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Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Mouse
- Derivation
- Humanized (from mouse)
- Type
- IgG1
- Specificity
- Tested positive against native human antigen.
- Species Reactivity
- Human
- Applications
- Suitable for use in ELISA, IP, FC, FuncS, Neut, IF, ICC and most other immunological methods.
- CAS
- 267227-08-7
- Generic Name
- Apolizumab
- UNII
- G88KCP51RE
- Related Disease
- Chronic lymphocytic leukemia (CLL) (refractory)
Product Property
- Purity
- >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
- Storage
- Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.
Target
- Alternative Names
- Apolizumab;267227-08-7;1D10;HU1D10;K8-355;HLA-DRB1;major histocompatibility complex, class II, DR beta 1;HLA DR1B;DW2.2/DR2.2;MHC class II antigen;lymphocyte antigen DRB1;MHC class II HLA-DRw10-beta;human leucocyte antigen DRB1;MHC class II HLA-DR beta 1
- Gene ID
- 3123
- UniProt ID
- P01911
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Biosimilar Overview
Please refer to Apolizumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Apolizumab.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "Apolizumab"
Afuco™ Anti-HLA-DRB1 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-150)This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to HLA DR beta.
DrugMonitor™ Anti-Apolizumab Antibody (VS-1224-YC107)Apolizumab is a humanized monoclonal antibody studied as a treatment for hematologic cancers. The DrugMonitor™ Anti-Apolizumab Antibody (VS-1224-YC107) is an anti-drug antibody (ADA) against Apolizumab. This drug-based antibody is raised in mice immunized with the Apolizumab. The anti-Apolizumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Apolizumab in samples.
See other products for "HLA-DRB1"
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| CAT | Product Name | Application | Type |
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| MOB-1090z-S(P) | Recombinant Anti-Human HLA-DRB1 Antibody scFv Fragment | WB, FC, FuncS | scFv |
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