Recombinant Mouse anti-Human JAK2 Monoclonal antibody (Z377)
CAT#: MOB-2300CT
Recombinant Mouse Monoclonall antibody to Human JAK2, expressed in Chinese Hamster Ovary cells(CHO).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm, plasma membrane & focal adhesion sites.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/43870/1338_A2_1_selected.jpg
Normal Tissue
Figure 2 IHC staining of human bone marrow
Immunohistochemical staining of human bone marrow shows moderate cytoplasmic and nuclear positivity in hematopoietic cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/40820/ihc_selected.jpg
Normal Tissue
Figure 3 IHC staining of human lymph node
Immunohistochemical staining of human lymph node shows strong cytoplasmic positivity in lymphoid tissue.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13089/ihc_selected.jpg
Normal Tissue
Figure 4 Cerebral cortex
Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13089/29841_B_7_5.jpg
Normal Tissue
Figure 5 Colon
Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13089/29841_A_9_3.jpg
Normal Tissue
Figure 6 Liver
Hepatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13089/29841_A_8_4.jpg
Normal Tissue
Figure 7 Kidney
Cells in glomeruli
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13089/29841_A_9_5.jpg
Normal Tissue
Figure 8 Testis
Cells in seminiferous ducts
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13089/29841_A_4_6.jpg
RNA Expression
Figure 9 RNA cell line category: Group enriched (ASC diff, HDLM-2, HEL)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000096968-JAK2
❮
❯
Specifications
- Immunogen
- Recombinant fragment from Human JAK2 expressed in E.coli.
- Host Species
- Mouse
- Specificity
- Expressed in blood, bone marrow and lymph node.
- Species Reactivity
- Human
- Clone
- Z377
- Applications
- Used for immunoassay techniques such as: Western Blot
- Conjugate
- Unconjugated
Product Property
- Purity
- Protein A purified
- Format
- Liquid
- Buffer
- Preservative: 0.1% Sodium Azide. Constituents: 1% BSA, PBS, pH 7.2
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Target
- Alternative Names
- JAK2; Janus kinase 2; JTK10; THCYT3; tyrosine-protein kinase JAK2; JAK-2; Janus kinase 2 (a protein tyrosine kinase);
- Gene ID
- 3717
- UniProt ID
- O60674
- Protein Refseq
- NP_004963
- Function
- ATP binding; SH2 domain binding; growth hormone receptor binding; heme binding; histone binding; histone kinase activity (H3-Y41 specific); interleukin-12 receptor binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; protei
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for MOB-2300CT. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Related Signaling Pathways
JAK-STAT Signaling Pathway
Related Diseases
Pancreatic Cancer
AGE-RAGE Signaling Pathway in Diabetic Complications
Maturity Onset Diabetes of the Young
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "JAK2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1898 | Hi-Affi™ Recombinant Rabbit Anti-JAK2 Monoclonal Antibody (DS1898AB) | WB, IHC-Fr, IHC-P, ICC, IP, Dot | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1986-CN | Rabbit Anti-JAK2 Polyclonal Antibody (MRO-1986-CN) | IF, IHC | Rabbit IgG |
| ZG-0779J | Rabbit Anti-JAK2 Recombinant Antibody (clone 1A4) | ELISA, WB, IHC, IP | Rabbit IgG |
| ZG-0780J | Rabbit Anti-JAK2 Recombinant Antibody (clone 10B6) | ELISA, IF | Rabbit IgG |
| VS4-WK260 | Mouse Anti-JAK2 Recombinant Antibody (VS4-WK260) | ELISA, IHC | Mouse IgG |
| VS3-WK2166 | Rabbit Anti-JAK2 (pY1007/pY1008) Recombinant Antibody (clone R02-1C5) | WB, IHC-P, ICC, IF, IP, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY162 | AbPlus™ Anti-JAK2 Magnetic Beads (CBACN-632) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC609 | CytoStream™ Mouse Anti-JAK2 Recombinant Antibody (VS13-YC609) | WB, ICC, IF, IHC-P, FC | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3687 | Anti-JAK2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3688 | Anti-Mouse JAK2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3689 | Anti-Rat JAK2 Immunohistochemistry Kit | IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: FC, IP, ELISA, Neut, FuncS, IF, IHC
Application: WB, IF, IP, Neut, FuncS, ELISA, FC
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: FuncS, IF, Neut, ELISA, FC, IP, IHC
Application: WB, ELISA, FC, IP, FuncS, IF, Neut
Application: IP, IF, FuncS, FC, Neut, ELISA, IHC
Application: Neut, ELISA, Inhib, ICC, WB
Application: SPR, Inhib, FuncS
Application: ELISA, FC, IF, WB
Application: ELISA, Inhib, FuncS
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
