Recombinant Mouse anti-Human JAK2 Monoclonal antibody (Z377) (CAT#: MOB-2300CT)
Recombinant Mouse Monoclonall antibody to Human JAK2, expressed in Chinese Hamster Ovary cells(CHO).
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm, plasma membrane & focal adhesion sites.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43870/1338_A2_1_selected.jpg

(Immunohistochemical staining of human bone marrow shows moderate cytoplasmic and nuclear positivity in hematopoietic cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/40820/ihc_selected.jpg

(Immunohistochemical staining of human lymph node shows strong cytoplasmic positivity in lymphoid tissue.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13089/ihc_selected.jpg

(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13089/29841_B_7_5.jpg

(Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13089/29841_A_9_3.jpg

(Hepatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13089/29841_A_8_4.jpg

(Cells in glomeruli
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13089/29841_A_9_5.jpg

(Cells in seminiferous ducts
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13089/29841_A_4_6.jpg

(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000096968-JAK2
Specifications
- Immunogen
- Recombinant fragment from Human JAK2 expressed in E.coli.
- Host Species
- Mouse
- Specificity
- Expressed in blood, bone marrow and lymph node.
- Species Reactivity
- Human
- Clone
- Z377
- Applications
- Used for immunoassay techniques such as: Western Blot
- Conjugate
- Unconjugated
Product Property
- Purity
- Protein A purified
- Format
- Liquid
- Buffer
- Preservative: 0.1% Sodium Azide. Constituents: 1% BSA, PBS, pH 7.2
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Target
- Alternative Names
- JAK2; Janus kinase 2; JTK10; THCYT3; tyrosine-protein kinase JAK2; JAK-2; Janus kinase 2 (a protein tyrosine kinase);
- Gene ID
- 3717
- UniProt ID
- O60674
- Protein Refseq
- NP_004963
- Function
- ATP binding; SH2 domain binding; growth hormone receptor binding; heme binding; histone binding; histone kinase activity (H3-Y41 specific); interleukin-12 receptor binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; protei
Related Resources
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "JAK2"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1898 | Hi-Affi™ Recombinant Rabbit Anti-JAK2 Monoclonal Antibody (DS1898AB) | WB, IHC-Fr, IHC-P, ICC, IP, Dot | IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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