Recombinant Mouse Anti-IAV HA heptapeptide (DVPDYAS) Antibody (17/9) (CAT#: PABZ-078)

Recombinant Mouse Antibody (17/9) is capable of binding to IAV HA heptapeptide (DVPDYAS), expressed in Chinese Hamster Ovary cells (CHO).

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ELISA

Figure 1 Profiles of reactivity of MAb 17/9 to cell lysates bearing WT or amino acid-substituted MPER-TM1 constructs.

Figure 1 Profiles of reactivity of MAb 17/9 to cell lysates bearing WT or amino acid-substituted MPER-TM1 constructs.

Constructs containing indicated single amino acid substitutions were expressed in COS-7 cells. Cells were lysed, and lysates were produced by sonication and immobilized in microtiter wells. These were probed with 10 nM MAb 17/9, which binds the HA tag (YPYDVPDYA) at the N terminus of each MPER construct. 17/9 MAb with goat (anti-mouse IgG)-HRP (1:1,000 dilution). Abs were diluted in TBS containing 5% NFDM and 0.1% Tween 20. Binding of Nt MAbs, normalized to HA expression in order to account for differences in cell surface expression, is expressed as a percentage of binding to the WT MPER-TM1 construct (black bar; dashed line).

Montero, M., Gulzar, N., Klaric, K. A., Donald, J. E., Lepik, C., Wu, S., ... & Scott, J. K. (2012). Neutralizing epitopes in the membrane-proximal external region of HIV-1 gp41 are influenced by the transmembrane domain and the plasma membrane. Journal of virology, 86(6), 2930-2941.


Specifications

  • Immunogen
  • IAV hemagglutinin
  • Host Species
  • Mouse
  • Derivation
  • Mouse
  • Type
  • IgG
  • Specificity
  • Tested positive against native IAV HA heptapeptide (DVPDYAS)
  • Species Reactivity
  • IAV
  • Clone
  • 17/9
  • Applications
  • Can be useful in applications such as: Enzyme-linked Immunosorbent Assay

Product Property

  • Purity
  • >95% by SDS-PAGE and HPLC analysis
  • Storage
  • Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

Target

  • Alternative Names
  • HA; hemagglutinin; HA1; HA2

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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See other products for "Clone 17/9"

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Humanized Antibody

CAT Product Name Application Type
PABX-070-S (P) Recombinant Mouse Anti-HA1 Antibody scFv Fragment (Fab17/9) WB, ELISA, Neut, FuncS scFv

Rabbit Monoclonal Antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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