Recombinant Human Anti-IAV HA Antibody (5J8) (CAT#: PABL-207)

Recombinant Human Antibody (5J8) is capable of binding to IAV HA, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-IAV HA mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-IAV HA mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.


Specific Inquiry
  • Size:
  • Conjugation:
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  • Purity:
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  • Published Data
  • Tested Data
  • Datasheet
  • MSDS
  • COA
FuncS

Figure 1 Therapeutic efficacy of MAb 5J8 against disease caused bythe 1918 influenza A(H1N1) virus in mice.

Figure 1 Therapeutic efficacy of MAb 5J8 against disease caused bythe 1918 influenza A(H1N1) virus in mice.

Mice were inoculated onday 0 and treated on day 1 with the indicated antibody and dose. In each group, six mice were monitored every other day for survival.

Krause, J. C., Tsibane, T., Tumpey, T. M., Huffman, C. J., Basler, C. F., & Crowe, J. E. (2011). A broadly neutralizing human monoclonal antibody that recognizes a conserved, novel epitope on the globular head of the influenza H1N1 virus hemagglutinin. Journal of virology, 85(20), 10905-10908.


Specifications

  • Immunogen
  • Influenza a virus Hemagglutinin
  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • IgG
  • Specificity
  • Tested positive against native IAV HA
  • Species Reactivity
  • IAV
  • Clone
  • 5J8
  • Applications
  • FuncS

Product Property

  • Purity
  • >95% by SDS-PAGE and HPLC analysis
  • Storage
  • Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

Applications

  • Application Notes
  • This antibody has been reported for use in Function Assay.

Target

  • Alternative Names
  • HA; hemagglutinin; haemagglutinin

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone 5J8"

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Humanized Antibody

CAT Product Name Application Type
PABX-070-S (P) Recombinant Mouse Anti-HA1 Antibody scFv Fragment (Fab17/9) WB, ELISA, Neut, FuncS scFv

Rabbit Monoclonal Antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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