Mouse Anti-IDH1 Recombinant Antibody (clone A2E8); Fab Fragment
CAT#: HPAB-0136-YC-F(E)
The antibody specifically recognizes human isocitrate dehydrogenase (IDHI1) R132H. The mutation site associates with malignant disease and plays a pathogenic role in the diagnosis and treatment, such as glioma and leukemia and other diseases.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nuclear bodies & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/62556/1538_D1_6_selected.jpg
Normal Tissue
Figure 2 Liver
Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35248/142542_A_7_4.jpg
Normal Tissue
Figure 3 Testis
Leydig cells Staining: High Intensity: Strong Quantity:>75% Sertoli cells Staining: Medium Intensity: Moderate Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35248/142542_A_6_6.jpg
Normal Tissue
Figure 4 Prostate
Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35248/142542_A_1_5.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (Hep G2, RT4)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000138413-IDH1
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Specifications
- Immunogen
- The synthetic peptide containing the IDHl R132H
- Host Species
- Mouse
- Type
- Mouse Fab
- Specificity
- Human IDH1
- Species Reactivity
- Human
- Clone
- A2E8
- Applications
- ELISA, WB
- Related Disease
- Glioma, Leukemia
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone A2E8"
- CAT
- Product Name
See other products for "IDH1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1615z | Mouse Anti-IDH1 Recombinant Antibody (clone 27C2) | WB, FC, IF, IHC | Mouse IgG1, κ |
| MRO-0876-CN | Mouse Anti-IDH1 Recombinant Antibody (clone A11-B4) | WB, IHC | Mouse IgG1 |
| VS3-FY721 | Recombinant Rabbit Anti-IDH1 Antibody (clone R05-2G5) | WB, IHC-P, IP | Rabbit IgG |
| VS7-0425-WR112 | Mouse Anti-IDH1 Recombinant Antibody (clone 4A4A8) | WB, FC | Mouse IgG1 |
| VS7-0425-WR113 | Mouse Anti-IDH1 Recombinant Antibody (clone 7G8A1) | WB, ICC, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1733 | Rabbit Anti-IDH1 Recombinant Antibody (clone DS1733AB) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0136-YC-S(P) | Mouse Anti-IDH1 Recombinant Antibody (clone A2E8); scFv Fragment | ELISA, WB | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC1486 | AbPlus™ Anti-IDH1 Magnetic Beads (VS-0724-YC1486) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY268 | Mouse Anti-NHP IDH1 Recombinant Antibody (clone OTI24A2) | WB, IHC | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1087 | Anti-IDH1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3383 | Anti-Mouse IDH1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3382 | Anti-Human IDH1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3384 | Anti-Rat IDH1 Immunohistochemistry Kit | IHC |
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