Mouse Anti-IDH1 Recombinant Antibody (clone A2E8); scFv Fragment (CAT#: HPAB-0136-YC-S(P))
The antibody specifically recognizes human isocitrate dehydrogenase (IDHI1) R132H. The mutation site associates with malignant disease and plays a pathogenic role in the diagnosis and treatment, such as glioma and leukemia and other diseases.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nuclear bodies & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/62556/1538_D1_6_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to nuclear bodies & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/62556/1538_D1_6_selected.jpg
Figure 2 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35248/142542_A_7_4.jpg
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35248/142542_A_7_4.jpg
Figure 3 Testis
(Leydig cells Staining: High Intensity: Strong Quantity:>75% Sertoli cells Staining: Medium Intensity: Moderate Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35248/142542_A_6_6.jpg
(Leydig cells Staining: High Intensity: Strong Quantity:>75% Sertoli cells Staining: Medium Intensity: Moderate Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35248/142542_A_6_6.jpg
Figure 4 Prostate
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35248/142542_A_1_5.jpg
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35248/142542_A_1_5.jpg
Figure 5 RNA cell line category: Cell line enhanced (Hep G2, RT4)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000138413-IDH1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000138413-IDH1
Specifications
- Immunogen
- The synthetic peptide containing the IDHl R132H
- Host Species
- Mouse
- Type
- Mouse scFv
- Specificity
- Human IDH1
- Species Reactivity
- Human
- Clone
- A2E8
- Applications
- ELISA, WB
- Related Disease
- Glioma, Leukemia
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IHC Kits & Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1615z | Mouse Anti-IDH1 Recombinant Antibody (clone 27C2) | WB, FC, IF, IHC | Mouse IgG1, κ |
| HPAB-0136-YC | Mouse Anti-IDH1 Recombinant Antibody (clone A2E8) | ELISA, WB, DB | Mouse IgG |
| MRO-0876-CN | Mouse Anti-IDH1 Recombinant Antibody (clone A11-B4) | WB, IHC | Mouse IgG1 |
| VS3-FY721 | Recombinant Rabbit Anti-IDH1 Antibody (clone R05-2G5) | WB, IHC-P, IP | Rabbit IgG |
| VS7-0425-WR112 | Mouse Anti-IDH1 Recombinant Antibody (clone 4A4A8) | WB, FC | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
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