Anti-Human IGFBP7 Therapeutic Single Domain Antibody (CAT#: TAB-388CL)
Recombinant Humanized monoclonal Single Domain Antibody expressed in E. coli binding to Human IGFBP7. The antibodiess specific for insulin-like growth factor binding protein-7 (IGFBP7) may be useful as diagnostic tools for detecting neoplastic diseases involving tumor angiogenesis, and a variety of other angiogenesis associated diseases.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/20668/if_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/20668/if_selected.jpg
Figure 2 IHC staining of human kidney
(Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in cells in tubules.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/ihc_selected.jpg
(Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in cells in tubules.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/ihc_selected.jpg
Figure 3 IHC staining of human pancreas
(Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in islet cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/20668/ihc_selected.jpg
(Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in islet cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/20668/ihc_selected.jpg
Figure 4 Cerebral cortex
(Neuronal cells
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/106599_B_7_5.jpg
(Neuronal cells
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/106599_B_7_5.jpg
Figure 5 Colon
(Glandular cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/106599_A_8_3.jpg
(Glandular cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/106599_A_8_3.jpg
Figure 6 Liver
(Hepatocytes
Staining: Not detected
Intensity:Weak
Quantity: <25%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/106599_A_8_4.jpg
(Hepatocytes
Staining: Not detected
Intensity:Weak
Quantity: <25%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/106599_A_8_4.jpg
Figure 7 Testis
(Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/106599_A_5_6.jpg
(Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/106599_A_5_6.jpg
Figure 8 Lymph node
(Non-germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/106599_A_8_8.jpg
(Non-germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/106599_A_8_8.jpg
Figure 9 RNA cell line category: Cell line enhanced (BJ, BJ hTERT+, hTERT-RPE1, RPTEC TERT1, TIME)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000163453-IGFBP7
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000163453-IGFBP7
Specifications
- Derivation
- Humanized
- Type
- Single Domain Antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- >90% assessed by SDS-PAGE
- Storage
- ≤6 months at 4°C; ≥6 months at -20°C.
Target
- Alternative Names
- IGFBP7; insulin-like growth factor binding protein 7; AGM; PSF; TAF; FSTL2; IBP-7; MAC25; IGFBP-7; RAMSVPS; IGFBP-7v; IGFBPRP1; insulin-like growth factor-binding protein 7; IGFBP-rP1; angiomodulin; IGF-binding protein 7; PGI2-stimulating factor; tumor-de
- Gene ID
- 3490
- UniProt ID
- Q16270
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "IGFBP7"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-546 | Recombinant Anti-human IGFBP7 Antibody | ELISA, WB, IF, FuncS | IgG |
| MOB-2258MZ | Recombinant Mouse Anti-Human IGFBP7 Antibody (clone NN0457-4O48) | WB | Mouse antibody |
| HPAB-0134-CN | Mouse Anti-IGFBP7 Recombinant Antibody (HPAB-0134-CN) | ELISA | Mouse IgG1, κ |
| HPAB-0135-CN | Mouse Anti-IGFBP7 Recombinant Antibody (HPAB-0135-CN) | WB, ELISA, Inhib, FuncS, IHC | Mouse IgG1, κ |
| VS3-XY848 | Mouse Anti-IGFBP7 Recombinant Antibody (clone 1D9) | ELISA, WB, IHC | Mouse IgG1 |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-546-F(E) | Recombinant Anti-human IGFBP7 Antibody Fab Fragment | WB, FACS, FuncS | Fab |
| MHH-546-F(E) | Recombinant Human Anti-human IGFBP7 Antibody Fab Fragment | ELISA, Nert, FuncS | Fab |
| HPAB-0134-CN-F(E) | Mouse Anti-IGFBP7 Recombinant Antibody; Fab Fragment (HPAB-0134-CN-F(E)) | ELISA | Mouse Fab |
| HPAB-0135-CN-F(E) | Mouse Anti-IGFBP7 Recombinant Antibody; Fab Fragment (HPAB-0135-CN-F(E)) | ELISA | Mouse Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-546-S(P) | Recombinant Anti-human IGFBP7 Antibody scFv Fragment | WB, ELISA, IHC, FuncS | scFv |
| MHH-546-S(P) | Recombinant Human Anti-human IGFBP7 Antibody scFv Fragment | ELISA, WB, FC, FuncS | scFv |
| HPAB-0134-CN-S(P) | Mouse Anti-IGFBP7 Recombinant Antibody; scFv Fragment (HPAB-0134-CN-S(P)) | ELISA | Mouse scFv |
| HPAB-0135-CN-S(P) | Mouse Anti-IGFBP7 Recombinant Antibody; scFv Fragment (HPAB-0135-CN-S(P)) | ELISA | Mouse scFv |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-097ZJ | Llama Anti-IGFBP7 Recombinant Antibody (TAB-097ZJ) | IHC, ELISA | Llama VHH |
| TAB-098ZJ | Llama Anti-IGFBP7 Recombinant Antibody (TAB-098ZJ) | ELISA, IHC, IF, FuncS | Llama VHH |
| HPAB-AP908-YC | Recombinant Lama glama Anti-IGFBP7 Single Domain Antibody (AP018/YC) | FuncS | Lama glama VHH |
| HPAB-AP909-YC | Recombinant Lama glama Anti-IGFBP7 Single Domain Antibody (AP019/YC) | FuncS | Lama glama VHH |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1762 | Rabbit Anti-IGFBP7 Recombinant Antibody (clone DS1762AB) | WB | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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