Afuco™ Anti-Human KLRC1 ADCC Recombinant Antibody (IPH 2201), ADCC Enhanced (CAT#: AFC-453CL)
Anti-KLRC1 ADCC Enhanced Antibody (IPH 2201) is an ADCC enhanced antibody produced by our Afuco™ platform. IPH2201 is a first-in-class humanized IgG4 targeting NKG2A receptors expressed on tumor infiltrating cytotoxic NK and CD8 T lymphocytes. IPH2201 may re-establish a broad anti-tumor response mediated by NK and T cells. IPH2201 may also enhance the cytotoxic potential of other therapeutic antibodies. IPH2201 is currently in Phase II development in various cancer indications and combinations.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/58052/1522_A10_3_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/58052/1522_A10_3_selected.jpg
Figure 2 RNA cell line category: Cell line enhanced (HeLa, Karpas-707)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000134545-KLRC1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000134545-KLRC1
Specifications
- Host Species
- Humanized
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Autoimmune Diseases; Inflammatory Diseases; Rheumatoid Arthritis
Product Property
- Purity
- >95% by HPLC
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- KLRC1; killer cell lectin-like receptor subfamily C, member 1; NKG2; NKG2A; CD159A; NKG2-A/NKG2-B type II integral membrane protein; NK cell receptor A; C-lectin type II protein; natural killer cell lectin; natural killer group protein 2; NKG2-1/B activating NK receptor; NKG2-A/B-activating NK receptor; CD159 antigen-like family member A; NKG2-A/B type II integral membrane protein
- Gene ID
- 3821
- UniProt ID
- P26715
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "KLRC1"
Select a product category from the dropdown menu below to view related products.
Please select product type
IgG Antibodies
Fab Antibodies
ScFv Antibodies
Humanized Antibodies
ADCC Enhanced Antibodies
ScFv-Fc Chimeras
Extracellular Vesicle Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-604 | Recombinant Anti-human KLRC1 Antibody | WB, Neut, FuncS | IgG |
| MHH-604 | Recombinant Human Anti-human KLRC1 Antibody | ELISA, WB, FC, FuncS | IgG |
| MOB-0225CT | Recombinant Mouse anti-Human KLRC1 Monoclonal antibody (NN0598-9T47) | WB | |
| MOR-1968 | Hi-Affi™ Recombinant Rabbit Anti-KLRC1 Monoclonal Antibody (DS1968AB) | IHC-P, WB | IgG |
| VS-0224-XY78 | Mouse Anti-KLRC1 Recombinant Antibody (VS-0224-XY78) | FC, IF, IHC | Mouse IgG2a |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for AFC-453CL. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: ELISA, Neut, IF, IP, FC, FuncS
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: Neut, ELISA, IF, IP, FuncS, FC, WB
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: FuncS, IF, Neut, ELISA, FC, IP, IHC
![Figure 2 Anti-Human CD19 Recombinant Antibody Fab Fragment [TAB-1611CL-F(E)] in HPLC](https://img.creativebiolabs.net/productimages/COA-TAB-1611CL-F(E)-2.png)
Application: Depletion, FuncS
Application: ELISA, IHC, FC, IP, IF, Inhib
Application: ELISA, Inhib, FuncS
Application: ELISA, WB, FC, IHC, IP
Application: ELISA, Inhib, FC, Neut
Application: ELISA, FC, Inhib, IHC-Fr, WB, IP
Application: IF, ICC, WB, IHC-P, IP
For Research Use Only. Not For Clinical Use.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
